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    CB5-A cytochrome B5 isoform A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839176, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CB5-A
    Official Full Name
    cytochrome B5 isoform A
    Primary source
    TAIR:AT1G26340
    Locus tag
    AT1G26340
    See related
    Araport:AT1G26340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS CYTOCHROME B5 ISOFORM A; ATCB5-A; B5 #6; cytochrome B5 isoform A; F28B23.1
    Summary
    encodes a member of the cytochromes b5 family of proteins that localizes to the outer envelope of the chloroplast. The C-terminal portion of the protein appears to be capable of inserting into a plant microsomal membrane in vitro.
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    Genomic context

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    See CB5-A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (9113864..9114977)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Zinc-binding dehydrogenase family protein Neighboring gene DNA binding protein Neighboring gene uncharacterized protein Neighboring gene SPIRAL1-like1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis sucrose transporter SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose. Li Y, et al. Mol Plant, 2012 Sep. PMID 22311778
    2. Functional association of cell death suppressor, Arabidopsis Bax inhibitor-1, with fatty acid 2-hydroxylation through cytochrome b₅. Nagano M, et al. Plant J, 2009 Apr. PMID 19054355
    3. Intracellular sorting of the tail-anchored protein cytochrome b5 in plants: a comparative study using different isoforms from rabbit and Arabidopsis. Maggio C, et al. J Exp Bot, 2007. PMID 17322552
    4. Association of cytochrome b5 with ETR1 ethylene receptor signaling through RTE1 in Arabidopsis. Chang J, et al. Plant J, 2014 Feb. PMID 24635651, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102398.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in stromule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome B5 isoform A
    NP_173958.1
    • cytochrome B5 isoform A (CB5-A); CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: cytochrome B5 isoform B (TAIR:AT2G32720.1); Has 4207 Blast hits to 4178 proteins in 465 species: Archae - 2; Bacteria - 26; Metazoa - 1058; Fungi - 1672; Plants - 799; Viruses - 3; Other Eukaryotes - 647 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9113864..9114977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102398.3 → NP_173958.1  cytochrome B5 isoform A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173958.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FDW8
      UniProtKB/TrEMBL
      A0A178WMK3, A0A5S9VZK2
      Conserved Domains (1) summary
      pfam00173
      Location:9 → 81
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FDW8.1

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