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    cpHsc70-1 chloroplast heat shock protein 70-1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828531, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cpHsc70-1
    Official Full Name
    chloroplast heat shock protein 70-1
    Primary source
    TAIR:AT4G24280
    Locus tag
    AT4G24280
    See related
    Araport:AT4G24280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chloroplast heat shock protein 70-1; T22A6.110; T22A6_110
    Summary
    Involved in protein import into chloroplasts during early developmental stages.
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    Genomic context

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    See cpHsc70-1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (12589810..12593800)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene EMBRYO DEFECTIVE 140 Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene MAC/Perforin domain-containing protein Neighboring gene Peptidase C50, separase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis stromal 70-kD heat shock proteins are essential for plant development and important for thermotolerance of germinating seeds. Su PH, et al. Plant Physiol, 2008 Mar. PMID 18192441, Free PMC Article
    2. Tissue-Specific Regulation of Plastid Protein Import via Transit-Peptide Motifs. Chu CC, et al. Plant Cell, 2020 Apr. PMID 32075863, Free PMC Article
    3. Functional analysis of the Chloroplast GrpE (CGE) proteins from Arabidopsis thaliana. de Luna-Valdez LA, et al. Plant Physiol Biochem, 2019 Jun. PMID 30927692
    4. Stromal Hsp70 is important for protein translocation into pea and Arabidopsis chloroplasts. Su PH, et al. Plant Cell, 2010 May. PMID 20484004, Free PMC Article
    5. Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family. Sung DY, et al. Plant Physiol, 2001 Jun. PMID 11402207, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. insertion knockout mutant plants exhibited variegated cotyledons, malformed leaves, growth retardation, and impaired root growth
      Title: Arabidopsis stromal 70-kD heat shock proteins are essential for plant development and important for thermotolerance of germinating seeds.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118561.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein folding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in intracellular anatomical structure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid stroma TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

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    Preferred Names
    chloroplast heat shock protein 70-1
    NP_194159.1
    • chloroplast heat shock protein 70-1 (cpHsc70-1); FUNCTIONS IN: protein binding, ATP binding; INVOLVED IN: protein folding, response to cadmium ion, protein targeting to chloroplast, response to cold; LOCATED IN: in 7 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Chaperone DnaK (InterPro:IPR012725), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: chloroplast heat shock protein 70-2 (TAIR:AT5G49910.1); Has 36155 Blast hits to 36031 proteins in 4857 species: Archae - 160; Bacteria - 17964; Metazoa - 3544; Fungi - 1694; Plants - 1235; Viruses - 354; Other Eukaryotes - 11204 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12589810..12593800
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118561.3 → NP_194159.1  chloroplast heat shock protein 70-1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194159.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9STW6
      UniProtKB/TrEMBL
      A0A178V345, A0A5S9XVD2
      Conserved Domains (1) summary
      PLN03184
      Location:40 → 716
      PLN03184; chloroplast Hsp70; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STW6.1

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