U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    SAE1A SUMO-activating enzyme 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828596, updated on 18-Sep-2024

    Summary

    Official Symbol
    SAE1A
    Official Full Name
    SUMO-activating enzyme 1A
    Primary source
    TAIR:AT4G24940
    Locus tag
    AT4G24940
    See related
    Araport:AT4G24940
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AT-SAE1-1; ATSAE1A; F13M23.80; F13M23_80; SUMO-activating enzyme 1A; SUMO-ACTIVATING ENZYME 1A
    Summary
    Encodes one of the two subunits of the SUMO activation enzyme required during sumolation. Sumolation is a post-translational protein modification process similar to ubiquitination during which a polypeptide (SUMO) is covalently attached to a target protein.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SAE1A in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    10
    Sequence:
    Chromosome: 4; NC_003075.7 (12823496..12826209)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene glucuronoxylan 4-O-methyltransferase-like protein (DUF579) Neighboring gene secE/sec61-gamma protein transport protein Neighboring gene thylakoid lumenal 17.9 kDa protein, chloroplast Neighboring gene uncharacterized protein Neighboring gene HVA22 homologue D

    Interactions

    General gene information

    NM_118626.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SUMO activating enzyme activity PubMed 
    enables SUMO activating enzyme activity PubMed 
    enables protein binding PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation  
    acts_upstream_of_or_within protein sumoylation PubMed 
    Component Evidence Code Pubs
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    SUMO-activating enzyme 1A
    NP_567712.1
    • SUMO-activating enzyme 1A (SAE1A); CONTAINS InterPro DOMAIN/s: UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: SUMO-activating enzyme 1B (TAIR:AT5G50580.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12823496..12826209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118626.3 → NP_567712.1  SUMO-activating enzyme 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567712.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY78, Q9SW32
      UniProtKB/TrEMBL
      A0A178UWC4, A0A5S9XVK9
      Conserved Domains (1) summary
      cd01492
      Location:11 → 314
      Aos1_SUMO; Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    External link. Please review our privacy policy.