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    DGK7 diacylglycerol kinase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829157, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DGK7
    Official Full Name
    diacylglycerol kinase 7
    Primary source
    TAIR:AT4G30340
    Locus tag
    AT4G30340
    See related
    Araport:AT4G30340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATDGK7; diacylglycerol kinase 7; F17I23.320; F17I23_320
    Summary
    encodes a diacylglycerol kinase. Applying a specific diacylglycerol kinase inhibitor to the growth media resulted in reduced root elongation and plant growth. Gene is expressed throughout the plant but is strongest in flowers and young seedlings.
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    Genomic context

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    See DGK7 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    9
    Sequence:
    Chromosome: 4; NC_003075.7 (14838172..14841147, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene CAP (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 protein) superfamily protein Neighboring gene Small nuclear ribonucleoprotein family protein Neighboring gene Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein Neighboring gene cyclic nucleotide-gated channel 17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development. Gómez-Merino FC, et al. J Biol Chem, 2005 Oct 14. PMID 16081412
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. molecular cloning and characterization of AtDGK7; phosphorylates diacylglycerol molecular species that are typically found in plants; expression is strongest in flowers and young seedlings
      Title: Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342006.1
    NM_119180.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    diacylglycerol kinase 7
    NP_567845.4
    • diacylglycerol kinase 7 (DGK7); FUNCTIONS IN: diacylglycerol kinase activity; INVOLVED IN: activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, root development, leaf development; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Diacylglycerol kinase, catalytic domain (InterPro:IPR001206), Diacylglycerol kinase, accessory domain (InterPro:IPR000756), Diacylglycerol kinase, plant (InterPro:IPR016961); BEST Arabidopsis thaliana protein match is: diacylglycerol kinase 3 (TAIR:AT2G18730.1); Has 1643 Blast hits to 1452 proteins in 227 species: Archae - 0; Bacteria - 189; Metazoa - 1007; Fungi - 0; Plants - 281; Viruses - 0; Other Eukaryotes - 166 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14838172..14841147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119180.6 → NP_567845.4  diacylglycerol kinase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567845.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0KYU1, F4JQ95, Q9C5L2, Q9M0C6
      UniProtKB/TrEMBL
      A0A178UUX1, A0A5S9XXL3, A0A7G2F795
      Conserved Domains (2) summary
      pfam00609
      Location:287 → 464
      DAGK_acc; Diacylglycerol kinase accessory domain
      pfam00781
      Location:94 → 234
      DAGK_cat; Diacylglycerol kinase catalytic domain

    2. NM_001342006.1 → NP_001328552.1  diacylglycerol kinase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B509
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JQ95.1

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