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    CIPK2 CBL-interacting protein kinase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830598, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CIPK2
    Official Full Name
    CBL-interacting protein kinase 2
    Primary source
    TAIR:AT5G07070
    Locus tag
    AT5G07070
    See related
    Araport:AT5G07070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CBL-interacting protein kinase 2; CBL-INTERACTING PROTEIN KINASE 2; SNF1-RELATED PROTEIN KINASE 3.2; SnRK3.2; T28J14.10; T28J14_10
    Summary
    Encodes CBL-interacting protein kinase 2 (CIPK2).
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    Genomic context

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    See CIPK2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (2196428..2198539, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene nodulin MtN21 /EamA-like transporter family protein Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene Ribosomal protein S4 (RPS4A) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel protein kinases associated with calcineurin B-like calcium sensors in Arabidopsis. Shi J, et al. Plant Cell, 1999 Dec. PMID 10590166, Free PMC Article
    2. Interaction specificity of Arabidopsis calcineurin B-like calcium sensors and their target kinases. Kim KN, et al. Plant Physiol, 2000 Dec. PMID 11115898, Free PMC Article
    3. Phosphorylation of calcineurin B-like (CBL) calcium sensor proteins by their CBL-interacting protein kinases (CIPKs) is required for full activity of CBL-CIPK complexes toward their target proteins. Hashimoto K, et al. J Biol Chem, 2012 Mar 9. PMID 22253446, Free PMC Article
    4. The NAF domain defines a novel protein-protein interaction module conserved in Ca2+-regulated kinases. Albrecht V, et al. EMBO J, 2001 Mar 1. PMID 11230129, Free PMC Article
    5. Comprehensive structural, interaction and expression analysis of CBL and CIPK complement during abiotic stresses and development in rice. Kanwar P, et al. Cell Calcium, 2014 Aug. PMID 24970010

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120789.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CBL-interacting protein kinase 2
    NP_196324.1
    • CBL-interacting protein kinase 2 (CIPK2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: signal transduction, protein amino acid phosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: stem, leaf whorl, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SOS3-interacting protein 1 (TAIR:AT5G58380.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2196428..2198539 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120789.3 → NP_196324.1  CBL-interacting protein kinase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196324.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LKD0, Q9LYQ8
      UniProtKB/TrEMBL
      A0A178URC7, A0A5S9Y235
      Conserved Domains (2) summary
      cd12195
      Location:315 → 428
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      cl21453
      Location:11 → 265
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LYQ8.1

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