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    TRP1 telomeric repeat binding protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836062, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TRP1
    Official Full Name
    telomeric repeat binding protein 1
    Primary source
    TAIR:AT5G59430
    Locus tag
    AT5G59430
    See related
    Araport:AT5G59430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTRP1; F2O15.20; F2O15_20; TELOMERE REPEAT BINDING PROTEIN 1; telomeric repeat binding protein 1
    Summary
    Encodes a telomeric repeat binding protein with a DNA binding domain at its C terminus. The DNA binding domain has a preference for GGTTTAG sequences and at least five of these repeats are required for recognition by a nearly full-length TRP1 protein.
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    Genomic context

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    See TRP1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (23967217..23970996)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene PGR5-like A protein Neighboring gene Rab5-interacting family protein Neighboring gene OSBP(oxysterol binding protein)-related protein 3C Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene GRAS family transcription factor Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A plant gene encoding a Myb-like protein that binds telomeric GGTTTAG repeats in vitro. Chen CM, et al. J Biol Chem, 2001 May 11. PMID 11278537
    2. AtTRP1 encodes a novel TPR protein that interacts with the ethylene receptor ERS1 and modulates development in Arabidopsis. Lin Z, et al. J Exp Bot, 2009. PMID 19567478, Free PMC Article
    3. Interactions of putative telomere-binding proteins in Arabidopsis thaliana: identification of functional TRF2 homolog in plants. Kuchar M, et al. FEBS Lett, 2004 Dec 17. PMID 15589838
    4. An armadillo-domain protein participates in a telomerase interaction network. Dokládal L, et al. Plant Mol Biol, 2018 Jul. PMID 29948659
    5. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtTRP1 interacted with the ERS1 and affects cross-talk between ethylene and auxin signalling.
      Title: AtTRP1 encodes a novel TPR protein that interacts with the ethylene receptor ERS1 and modulates development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_001085301.1
    NM_001085302.1
    NM_001345351.1
    NM_125334.4
    NM_180890.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables double-stranded telomeric DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ethylene-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    telomeric repeat binding protein 1
    NP_001078770.1
    • TELOMERE REPEAT BINDING PROTEIN 1 (ATTRP1); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Ubiquitin supergroup (InterPro:IPR019955), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: TRF-like 1 (TAIR:AT3G46590.2); Has 323 Blast hits to 308 proteins in 41 species: Archae - 0; Bacteria - 0; Metazoa - 9; Fungi - 0; Plants - 289; Viruses - 0; Other Eukaryotes - 25 (source: NCBI BLink).
    NP_001078771.1
    • TELOMERE REPEAT BINDING PROTEIN 1 (ATTRP1); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Ubiquitin supergroup (InterPro:IPR019955), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: TRF-like 1 (TAIR:AT3G46590.1); Has 326 Blast hits to 311 proteins in 42 species: Archae - 0; Bacteria - 0; Metazoa - 10; Fungi - 0; Plants - 290; Viruses - 0; Other Eukaryotes - 26 (source: NCBI BLink).
    NP_200751.1
    • TELOMERE REPEAT BINDING PROTEIN 1 (ATTRP1); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Ubiquitin supergroup (InterPro:IPR019955), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: TRF-like 1 (TAIR:AT3G46590.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_851221.1
    • telomeric repeat binding protein 1 (TRP1); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Ubiquitin supergroup (InterPro:IPR019955), Homeodomain-related (InterPro:IPR012287), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930); BEST Arabidopsis thaliana protein match is: TRF-like 1 (TAIR:AT3G46590.2); Has 326 Blast hits to 311 proteins in 42 species: Archae - 0; Bacteria - 0; Metazoa - 10; Fungi - 0; Plants - 290; Viruses - 0; Other Eukaryotes - 26 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23967217..23970996
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125334.4 → NP_200751.1  telomeric repeat binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200751.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQF8, A8MQM5, B9DFI1, C0Z2L6, Q8L7L8, Q9LTI6, Q9XGN0
      UniProtKB/TrEMBL
      A0A5S9YFI8, A0A654GDJ9
      Conserved Domains (2) summary
      cd11660
      Location:470 → 519
      SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
      cd17039
      Location:295 → 364
      Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins

    2. NM_001085302.1 → NP_001078771.1  telomeric repeat binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078771.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YFI8
      Conserved Domains (3) summary
      smart00717
      Location:469 → 519
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11660
      Location:469 → 518
      SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
      cl00155
      Location:306 → 363
      UBQ; Ubiquitin-like proteins

    3. NM_001085301.1 → NP_001078770.1  telomeric repeat binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078770.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9YFI8
      Conserved Domains (3) summary
      smart00717
      Location:470 → 520
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11660
      Location:470 → 519
      SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
      cl00155
      Location:307 → 364
      UBQ; Ubiquitin-like proteins

    4. NM_180890.1 → NP_851221.1  telomeric repeat binding protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851221.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQF8, A8MQM5, B9DFI1, C0Z2L6, Q8L7L8, Q9LTI6, Q9XGN0
      UniProtKB/TrEMBL
      A0A5S9YFI8, A0A654GDJ9
      Conserved Domains (2) summary
      cd11660
      Location:470 → 519
      SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
      cd17039
      Location:295 → 364
      Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins

    5. NM_001345351.1 → NP_001331960.1  telomeric repeat binding protein 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQF8, A8MQM5, B9DFI1, C0Z2L6, Q8L7L8, Q9LTI6, Q9XGN0
      UniProtKB/TrEMBL
      A0A5S9YFI8, A0A654GDJ9
      Conserved Domains (2) summary
      cd11660
      Location:470 → 519
      SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
      cd17039
      Location:295 → 364
      Ubl_ubiquitin_like; ubiquitin-like (Ubl) domain found in ubiquitin and ubiquitin-like Ubl proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7L8.2

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