NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001286521.2 → NP_001273450.1 protein mono-ADP-ribosyltransferase PARP11 isoform b
See identical proteins and their annotated locations for NP_001273450.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an exon in the 5' coding region and initiates translation at an alternate downstream start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform 1. Variants 2 and 3 encode the same isoform (b).
- Source sequence(s)
-
AC006207, AK299372, BX953946
- Consensus CDS
-
CCDS66281.1
- UniProtKB/Swiss-Prot
-
Q9NR21
- Related
- ENSP00000405385.3, ENST00000447133.7
- Conserved Domains (1) summary
-
- cd01439
Location:120 → 256
- TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
-
NM_001286522.2 → NP_001273451.1 protein mono-ADP-ribosyltransferase PARP11 isoform b
See identical proteins and their annotated locations for NP_001273451.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) contains an alternate exon and lacks an exon in the 5' coding region, and initiates translation at an alternate downstream start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform 1. Variants 2 and 3 encode the same isoform (b).
- Source sequence(s)
-
AC005842, AC006207, BX953946
- Consensus CDS
-
CCDS66281.1
- UniProtKB/Swiss-Prot
-
Q9NR21
- Related
- ENSP00000397058.2, ENST00000427057.6
- Conserved Domains (1) summary
-
- cd01439
Location:120 → 256
- TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
-
NM_020367.6 → NP_065100.2 protein mono-ADP-ribosyltransferase PARP11 isoform a
See identical proteins and their annotated locations for NP_065100.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (a).
- Source sequence(s)
-
AC006207, BC017569, BX953946
- Consensus CDS
-
CCDS8523.2
- UniProtKB/Swiss-Prot
- B4DRQ0, F8WBZ7, Q68DS1, Q8N5Y9, Q9NR21
- Related
- ENSP00000228820.4, ENST00000228820.9
- Conserved Domains (2) summary
-
- smart00678
Location:34 → 114
- WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
- cd01439
Location:201 → 337
- TCCD_inducible_PARP_like; Poly(ADP-ribose) polymerases catalyse the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a regulatory component ...
RNA
-
NR_104461.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC006207, AK314916, BX953946
- Related
-
ENST00000458162.6