Zfp81 zinc finger protein 81 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Zfp81provided by RGD
Official Full Name: zinc finger protein 81provided by RGD
Primary source: RGD:1583951
See related: EnsemblRapid:ENSRNOG00000069530 AllianceGenome:RGD:1583951
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF559 (zinc finger protein 559). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 50.5), Brain (RPKM 41.0) and 9 other tissues See more
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Genomic context

Location:: 7q11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (13294967..13327636, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (12644561..12672579, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (15817246..15826217, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Zfp101 (e-PCR), detects polymorphism
- UniSTS:463438

RH143541 (e-PCR)
- UniSTS:232787

RH131094 (e-PCR)
- UniSTS:214377

RH140930 (e-PCR)
- UniSTS:214377

AW531951 (e-PCR)
- UniSTS:245136

AU046625 (e-PCR)
- UniSTS:111276

Zfp101 (e-PCR), detects polymorphism
- UniSTS:527612

Homology

Orthologs from OrthoDB

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein 709-like

Names: Zinc finger protein 81-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086025.1 Reference GRCr8

Range

13294967..13327636 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039080057.2 → XP_038935985.1 zinc finger protein 709-like isoform X1

UniProtKB/TrEMBL

A0A8I5ZS44

Related

ENSRNOP00000081081.1, ENSRNOT00000104614.2

Conserved Domains (4) summary

COG5048
Location:277 → 437

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:364 → 384

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:3 → 44

KRAB; KRAB box

pfam13465
Location:488 → 513

zf-H2C2_2; Zinc-finger double domain
XM_063264495.1 → XP_063120565.1 zinc finger protein 709-like isoform X2

UniProtKB/TrEMBL

A0A8I5Y0W9