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    APG10 Aldolase-type TIM barrel family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818195, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APG10
    Official Full Name
    Aldolase-type TIM barrel family protein
    Primary source
    TAIR:AT2G36230
    Locus tag
    AT2G36230
    See related
    Araport:AT2G36230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALBINO AND PALE GREEN 10; BBM II ISOMERASE; F2H17.16; F2H17_16; HISN3; PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE
    Summary
    Encodes a BBMII isomerase involved in histidine biosynthesis.
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    Genomic context

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    See APG10 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (15193694..15195558, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene pentatricopeptide (PPR) repeat-containing protein Neighboring gene Tubulin/FtsZ family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ALBINO AND PALE GREEN 10 encodes BBMII isomerase involved in histidine biosynthesis in Arabidopsis thaliana. Noutoshi Y, et al. Plant Cell Physiol, 2005 Jul. PMID 15870096
    2. Molecular cloning and characterization of the gene encoding N'-[(5'-phosphoribosyl)-formimino]-5-aminoimidazole-4-carboxamide ribonucleotide (BBM II) isomerase from Arabidopsis thaliana. Fujimori K, et al. Mol Gen Genet, 1998 Aug. PMID 9747713
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_129181.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-histidine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in L-histidine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Aldolase-type TIM barrel family protein
    NP_181165.1
    • ALBINO AND PALE GREEN 10 (APG10); FUNCTIONS IN: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity; INVOLVED IN: histidine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060), Histidine biosynthesis (InterPro:IPR006062), Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, eukaryotic (InterPro:IPR011858); Has 5178 Blast hits to 5176 proteins in 1344 species: Archae - 226; Bacteria - 3159; Metazoa - 0; Fungi - 140; Plants - 59; Viruses - 0; Other Eukaryotes - 1594 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      15193694..15195558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129181.4 → NP_181165.1  Aldolase-type TIM barrel family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82782
      UniProtKB/TrEMBL
      A0A5S9X4E4, A0A654F0R4, Q5TKS8
      Conserved Domains (1) summary
      PLN02446
      Location:44 → 302
      PLN02446; (5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82782.1

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