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    ATKDSA2 Aldolase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838203, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ATKDSA2
    Official Full Name
    Aldolase superfamily protein
    Primary source
    TAIR:AT1G16340
    Locus tag
    AT1G16340
    See related
    Araport:AT1G16340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtKDO8PS; ATKSDA; F3O9.14; F3O9_14
    Summary
    Encodes a protein with putative 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity. This gene share a very high sequence homology with its homologue AtkdsA1 (AT1G79500).
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    Genomic context

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    See ATKDSA2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (5587722..5590761, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene plant/protein (DUF2358) Neighboring gene cyclin b3;1 Neighboring gene Aldolase-type TIM barrel family protein Neighboring gene LEM3 (ligand-effect modulator 3) family protein / CDC50 family protein Neighboring gene organic cation/carnitine transporter 6 Neighboring gene Cation/hydrogen exchanger family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The synthesis of the rhamnogalacturonan II component 3-deoxy-D-manno-2-octulosonic acid (Kdo) is required for pollen tube growth and elongation. Delmas F, et al. J Exp Bot, 2008. PMID 18503041, Free PMC Article
    2. Arabidopsis 3-deoxy-D-manno-oct-2-ulosonate-8-phosphate synthase: cDNA cloning and expression analyses. Matsuura K, et al. J Exp Bot, 2003 Jul. PMID 12754267
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Haploid pollens of the AtkdsA1 and AtkdsA2 double mutant can not form elongated pollen tube properly.
      Title: The synthesis of the rhamnogalacturonan II component 3-deoxy-D-manno-2-octulosonic acid (Kdo) is required for pollen tube growth and elongation.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001035978.2
    NM_001084078.1
    NM_001198082.1
    NM_101500.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-deoxy-8-phosphooctulonate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 3-deoxy-8-phosphooctulonate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monosaccharide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pollen tube development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within rhamnogalacturonan II biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in rhamnogalacturonan II biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Aldolase superfamily protein
    NP_001031055.1
    • ATKDSA2; FUNCTIONS IN: 3-deoxy-8-phosphooctulonate synthase activity; INVOLVED IN: metabolic process, rhamnogalacturonan II biosynthetic process; LOCATED IN: endomembrane system, cytoplasm; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase I/KDSA (InterPro:IPR006218), Aldolase-type TIM barrel (InterPro:IPR013785), 3-deoxy-8-phosphooctulonate synthase (InterPro:IPR006269); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT1G79500.4); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001077547.1
    • ATKDSA2; FUNCTIONS IN: 3-deoxy-8-phosphooctulonate synthase activity; INVOLVED IN: metabolic process, rhamnogalacturonan II biosynthetic process; LOCATED IN: endomembrane system, cytoplasm; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase I/KDSA (InterPro:IPR006218), Aldolase-type TIM barrel (InterPro:IPR013785), 3-deoxy-8-phosphooctulonate synthase (InterPro:IPR006269); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT1G79500.4); Has 7899 Blast hits to 7897 proteins in 2055 species: Archae - 64; Bacteria - 4967; Metazoa - 4; Fungi - 0; Plants - 58; Viruses - 0; Other Eukaryotes - 2806 (source: NCBI BLink).
    NP_001185011.1
    • ATKDSA2; FUNCTIONS IN: 3-deoxy-8-phosphooctulonate synthase activity; INVOLVED IN: metabolic process, rhamnogalacturonan II biosynthetic process; LOCATED IN: endomembrane system, cytoplasm; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase I/KDSA (InterPro:IPR006218), Aldolase-type TIM barrel (InterPro:IPR013785), 3-deoxy-8-phosphooctulonate synthase (InterPro:IPR006269); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT1G79500.4).
    NP_173084.1
    • ATKDSA2; FUNCTIONS IN: 3-deoxy-8-phosphooctulonate synthase activity; INVOLVED IN: metabolic process, rhamnogalacturonan II biosynthetic process; LOCATED IN: endomembrane system, cytoplasm; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DAHP synthetase I/KDSA (InterPro:IPR006218), Aldolase-type TIM barrel (InterPro:IPR013785), 3-deoxy-8-phosphooctulonate synthase (InterPro:IPR006269); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT1G79500.4); Has 7899 Blast hits to 7897 proteins in 2055 species: Archae - 64; Bacteria - 4967; Metazoa - 4; Fungi - 0; Plants - 58; Viruses - 0; Other Eukaryotes - 2806 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5587722..5590761 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001035978.2 → NP_001031055.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031055.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NQL4, Q9SA33
      UniProtKB/TrEMBL
      A0A178W4E1, A0A654EBD7
      Conserved Domains (1) summary
      PLN03033
      Location:2 → 291
      PLN03033; 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional

    2. NM_101500.4 → NP_173084.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173084.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NQL4, Q9SA33
      UniProtKB/TrEMBL
      A0A178W4E1, A0A654EBD7
      Conserved Domains (1) summary
      PLN03033
      Location:2 → 291
      PLN03033; 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional

    3. NM_001198082.1 → NP_001185011.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185011.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EBD7, F4I2W6
      Conserved Domains (1) summary
      PLN03033
      Location:2 → 293
      PLN03033; 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional

    4. NM_001084078.1 → NP_001077547.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077547.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NQL4, Q9SA33
      UniProtKB/TrEMBL
      A0A178W4E1, A0A654EBD7
      Conserved Domains (1) summary
      PLN03033
      Location:2 → 291
      PLN03033; 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NQL4.1

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