NADP-ME4 NADP-malic enzyme 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NADP-ME4
Official Full Name: NADP-malic enzyme 4
Primary source: TAIR:AT1G79750
Locus tag: AT1G79750
See related: Araport:AT1G79750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Arabidopsis thaliana NADP-malic enzyme 4; ATNADP-ME4; F19K16.27; F19K16_27; NADP-malic enzyme 4
Summary: The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME4 is localized to chloroplasts. The gene is expressed throughout the whole plant and during embryogenesis and germination. A possible involvement in the fatty acid biosynthesis has been proposed.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_106624.5

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables cobalt ion binding	HDA more info	PubMed
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IDA Inferred from Direct Assay more info	PubMed
enables oxaloacetate decarboxylase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	HDA more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid biosynthetic process	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within malate metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within malate metabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in mitochondrion	HDA more info	PubMed

NP_178093.1

NADP-malic enzyme 4 (NADP-ME4); CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NADP-malic enzyme 3 (TAIR:AT5G25880.1); Has 9573 Blast hits to 9553 proteins in 2441 species: Archae - 143; Bacteria - 6332; Metazoa - 610; Fungi - 220; Plants - 473; Viruses - 0; Other Eukaryotes - 1795 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain