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    PHB4 prohibitin 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822347, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PHB4
    Official Full Name
    prohibitin 4
    Primary source
    TAIR:AT3G27280
    Locus tag
    AT3G27280
    See related
    Araport:AT3G27280
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPHB4; prohibitin 4
    Summary
    Part of protein complexes that are necessary for proficient mitochondrial function or biogenesis, thereby supporting cell division and differentiation in apical tissues
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    Genomic context

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    See PHB4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (10076809..10078608)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene global transcription factor group E8 Neighboring gene TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein Neighboring gene miscRNA Neighboring gene RNI-like superfamily protein Neighboring gene glucose-6-phosphate dehydrogenase 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Presequence translocase-associated motor subunits of the mitochondrial protein import apparatus are dual-targeted to mitochondria and plastids. Gill-Hille M, et al. Front Plant Sci, 2022. PMID 36438081, Free PMC Article
    2. Mitochondrial type-I prohibitins of Arabidopsis thaliana are required for supporting proficient meristem development. Van Aken O, et al. Plant J, 2007 Dec. PMID 17883375
    3. Resolving and identifying protein components of plant mitochondrial respiratory complexes using three dimensions of gel electrophoresis. Meyer EH, et al. J Proteome Res, 2008 Feb. PMID 18189341
    4. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article
    5. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113642.4
    NM_202640.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex I HDA PubMed 

    General protein information

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    Preferred Names
    prohibitin 4
    NP_189364.1
    • prohibitin 4 (PHB4); INVOLVED IN: response to stress; LOCATED IN: in 6 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prohibitin (InterPro:IPR000163), Band 7 protein (InterPro:IPR001107); BEST Arabidopsis thaliana protein match is: prohibitin 3 (TAIR:AT5G40770.1); Has 5142 Blast hits to 5142 proteins in 1589 species: Archae - 203; Bacteria - 3017; Metazoa - 622; Fungi - 283; Plants - 261; Viruses - 12; Other Eukaryotes - 744 (source: NCBI BLink).
    NP_974369.1
    • prohibitin 4 (PHB4); INVOLVED IN: response to stress; LOCATED IN: mitochondrion, plasma membrane, vacuole, respiratory chain complex I, plant-type cell wall; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prohibitin (InterPro:IPR000163), Band 7 protein (InterPro:IPR001107); BEST Arabidopsis thaliana protein match is: prohibitin 3 (TAIR:AT5G40770.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10076809..10078608
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113642.4 → NP_189364.1  prohibitin 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189364.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84WL7, Q8LBC7, Q9LK25
      UniProtKB/TrEMBL
      A0A178VIY4, A0A5S9XG38
      Conserved Domains (2) summary
      cd03401
      Location:32 → 226
      SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
      cl23750
      Location:213 → 254
      vATP-synt_E; ATP synthase (E/31 kDa) subunit

    2. NM_202640.2 → NP_974369.1  prohibitin 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974369.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84WL7, Q8LBC7, Q9LK25
      UniProtKB/TrEMBL
      A0A178VIY4, A0A5S9XG38
      Conserved Domains (2) summary
      cd03401
      Location:32 → 226
      SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
      cl23750
      Location:213 → 254
      vATP-synt_E; ATP synthase (E/31 kDa) subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LK25.1

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