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    tRNA synthetase class I (I, L, M and V) family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826624, updated on 18-Sep-2024

    Summary

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    Official Full Name
    tRNA synthetase class I (I, L, M and V) family protein
    Primary source
    TAIR:AT4G10320
    Locus tag
    AT4G10320
    See related
    Araport:AT4G10320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F24G24.120; F24G24_120
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    25
    Sequence:
    Chromosome: 4; NC_003075.7 (6397271..6404672, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene reverse transcriptase Neighboring gene high-affinity K+ transporter 1 Neighboring gene glycine-rich protein Neighboring gene light harvesting complex of photosystem II 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_117100.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminoacyl-tRNA editing activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isoleucine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in isoleucyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tRNA synthetase class I (I, L, M and V) family protein
    NP_192770.2
    • tRNA synthetase class I (I, L, M and V) family protein; FUNCTIONS IN: isoleucine-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, zinc ion binding, ATP binding; INVOLVED IN: response to cadmium ion, tRNA aminoacylation for protein translation; LOCATED IN: cytosol; EXPRESSED IN: male gametophyte, guard cell, epidermis, cultured cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Isoleucyl-tRNA synthetase (InterPro:IPR018353), Isoleucyl-tRNA synthetase, class Ia (InterPro:IPR002301), Aminoacyl-tRNA synthetase, class 1a, anticodon-binding (InterPro:IPR009080), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Isoleucyl-tRNA synthetase, class Ia, N-terminal (InterPro:IPR015905), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR013155), Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing (InterPro:IPR009008), Aminoacyl-tRNA synthetase, class Ia (InterPro:IPR002300); BEST Arabidopsis thaliana protein match is: tRNA synthetase class I (I, L, M and V) family protein (TAIR:AT5G49030.3); Has 38868 Blast hits to 32849 proteins in 3074 species: Archae - 1055; Bacteria - 22228; Metazoa - 780; Fungi - 735; Plants - 304; Viruses - 0; Other Eukaryotes - 13766 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      6397271..6404672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117100.4 → NP_192770.2  tRNA synthetase class I (I, L, M and V) family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192770.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JLM5, O82613, Q9SV89
      UniProtKB/TrEMBL
      A0A5S9XR98
      Conserved Domains (4) summary
      cd07961
      Location:672 → 858
      Anticodon_Ia_Ile_ABEc; Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases
      cd00818
      Location:436 → 672
      IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
      PLN02882
      Location:3 → 1186
      PLN02882; aminoacyl-tRNA ligase
      cl00015
      Location:40 → 182
      nt_trans; nucleotidyl transferase superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JLM5.1

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