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    WRKY28 WRKY DNA-binding protein 28 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827542, updated on 18-Sep-2024

    Summary

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    Official Symbol
    WRKY28
    Official Full Name
    WRKY DNA-binding protein 28
    Primary source
    TAIR:AT4G18170
    Locus tag
    AT4G18170
    See related
    Araport:AT4G18170
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATWRKY28; T9A21.10; T9A21_10; WRKY DNA-binding protein 28
    Summary
    member of WRKY Transcription Factor; Group II-c. Involved in the activation of salicylic acid biosynthesis genes ICS1 and PBS3.
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    Genomic context

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    See WRKY28 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (10061214..10062893)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Serine/Threonine-kinase, putative (DUF1296) Neighboring gene Ca2+ activated outward rectifying K+ channel 6 Neighboring gene Pectin lyase-like superfamily protein Neighboring gene purine permease 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. KLU suppresses megasporocyte cell fate through SWR1-mediated activation of WRKY28 expression in Arabidopsis. Zhao L, et al. Proc Natl Acad Sci U S A, 2018 Jan 16. PMID 29288215, Free PMC Article
    2. Overexpression of AtWRKY28 and AtWRKY75 in Arabidopsis enhances resistance to oxalic acid and Sclerotinia sclerotiorum. Chen X, et al. Plant Cell Rep, 2013 Oct. PMID 23749099
    3. Co-expression of AtbHLH17 and AtWRKY28 confers resistance to abiotic stress in Arabidopsis. Babitha KC, et al. Transgenic Res, 2013 Apr. PMID 22948308
    4. Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 Integrates Age and Light Signals to Negatively Regulate Leaf Senescence. Tian T, et al. Plant Cell, 2020 May. PMID 32152188, Free PMC Article
    5. WRKY transcription factors involved in activation of SA biosynthesis genes. van Verk MC, et al. BMC Plant Biol, 2011 May 19. PMID 21595875, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These findings show how somatic cells in ovule primordia cooperatively use chromatin remodeling to restrict germ-line cell specification to a single cell.
      Title: KLU suppresses megasporocyte cell fate through SWR1-mediated activation of WRKY28 expression in Arabidopsis.
    2. Transgenic lines overexpressing AtWRKY28 and AtWRKY75 showed enhanced resistance to oxalic acid and S. sclerotiorum, demonstrating that both AtWRKY28 and AtWRKY75 are novel positive regulators in Arabidopsis defense responses.
      Title: Overexpression of AtWRKY28 and AtWRKY75 in Arabidopsis enhances resistance to oxalic acid and Sclerotinia sclerotiorum.
    3. A few genes having either WRKY or bHLH cis elements in their promoter regions showed higher transcript levels than wild type.
      Title: Co-expression of AtbHLH17 and AtWRKY28 confers resistance to abiotic stress in Arabidopsis.
    4. WRKY28 specifically binds to the ICS1 promoter in vivo, most probably to one or both binding sites at position -460 and -445 upstream of the transcription start site.
      Title: WRKY transcription factors involved in activation of SA biosynthesis genes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_117927.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of leaf senescence IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    WRKY DNA-binding protein 28
    NP_193551.1
    • WRKY DNA-binding protein 28 (WRKY28); CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657), Transcription factor, WRKY group IIc (InterPro:IPR017396); BEST Arabidopsis thaliana protein match is: WRKY DNA-binding protein 8 (TAIR:AT5G46350.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10061214..10062893
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117927.3 → NP_193551.1  WRKY DNA-binding protein 28 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193551.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49720, Q8VWJ2
      UniProtKB/TrEMBL
      A0A178V3M3, A0A5S9XTM8
      Conserved Domains (1) summary
      smart00774
      Location:171 → 228
      WRKY; DNA binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VWJ2.1

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