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    CRK28 cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827892, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRK28
    Official Full Name
    cysteine-rich RLK (RECEPTOR-like protein kinase) 28
    Primary source
    TAIR:AT4G21400
    Locus tag
    AT4G21400
    See related
    Araport:AT4G21400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cysteine-rich RLK (RECEPTOR-like protein kinase) 28; F18E5.20
    Summary
    Encodes a cysteine-rich receptor-like protein kinase.
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    Genomic context

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    See CRK28 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (11398857..11402180, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene receptor kinase 3 Neighboring gene S-locus lectin protein kinase family protein Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 29 Neighboring gene miscRNA Neighboring gene pseudo Neighboring gene protein B160

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Cysteine-Rich Protein Kinase Associates with a Membrane Immune Complex and the Cysteine Residues Are Required for Cell Death. Yadeta KA, et al. Plant Physiol, 2017 Jan. PMID 27852951, Free PMC Article
    2. An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response. Carianopol CS, et al. Commun Biol, 2020 Mar 26. PMID 32218501, Free PMC Article
    3. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, et al. Dev Cell, 2014 May 12. PMID 24823379
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CRK28 is associated with a membrane immune complex and the cysteine residues are required for cell death.
      Title: A Cysteine-Rich Protein Kinase Associates with a Membrane Immune Complex and the Cysteine Residues Are Required for Cell Death.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001341480.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cysteine-rich RLK (RECEPTOR-like protein kinase) 28
    NP_001320019.1
    • cysteine-rich RLK (RECEPTOR-like protein kinase) 28 (CRK28); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Protein of unknown function DUF26 (InterPro:IPR002902), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 29 (TAIR:AT4G21410.1); Has 113926 Blast hits to 112559 proteins in 4362 species: Archae - 99; Bacteria - 12248; Metazoa - 42120; Fungi - 9484; Plants - 33287; Viruses - 404; Other Eukaryotes - 16284 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      11398857..11402180 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341482.1 → NP_001328835.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5V9

    2. NM_001341481.1 → NP_001328834.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5W7, A0A654FRE0

    3. NM_001341485.1 → NP_001328838.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5U6

    4. NM_001341484.1 → NP_001328837.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5U6

    5. NM_001341483.1 → NP_001328836.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5U6

    6. NM_001341486.1 → NP_001328839.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5W4, A7Y5X2

    7. NM_001341487.1 → NP_001328840.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5W3, A7Y5X2

    8. NM_001341480.1 → NP_001320019.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 28 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JJI2, O65405
      UniProtKB/TrEMBL
      A0A654FRE0
      Conserved Domains (3) summary
      cd14066
      Location:367 → 636
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam00069
      Location:361 → 631
      Pkinase; Protein kinase domain
      pfam01657
      Location:40 → 132
      Stress-antifung; Salt stress response/antifungal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O65405.2

    Gene LinkOut

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