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    ROP10 RHO-related protein from plants 10 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823959, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROP10
    Official Full Name
    RHO-related protein from plants 10
    Primary source
    TAIR:AT3G48040
    Locus tag
    AT3G48040
    See related
    Araport:AT3G48040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis RAC-like 8; ARAC8; ATRAC8; ATROP10; RHO-related protein from plants 10; RHO-RELATED PROTEIN FROM PLANTS 10
    Summary
    Encodes a member of the Rop subfamily of Rho GTPases in Arabidopsis that contains a putative farnesylation motif. It is localized to the plasma membrane and involved in the negative regulation of ABA signalling.
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    Genomic context

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    See ROP10 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (17731337..17733513)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene hypoxia-responsive family protein / zinc finger (C3HC4-type RING finger) family protein Neighboring gene ncRNA Neighboring gene protein SUO Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasma membrane-associated ROP10 small GTPase is a specific negative regulator of abscisic acid responses in Arabidopsis. Zheng ZL, et al. Plant Cell, 2002 Nov. PMID 12417701, Free PMC Article
    2. Association of Arabidopsis type-II ROPs with the plasma membrane requires a conserved C-terminal sequence motif and a proximal polybasic domain. Lavy M, et al. Plant J, 2006 Jun. PMID 16805728
    3. A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes. Basu D, et al. Proc Natl Acad Sci U S A, 2008 Mar 11. PMID 18308939, Free PMC Article
    4. Analysis of the small GTPase gene superfamily of Arabidopsis. Vernoud V, et al. Plant Physiol, 2003 Mar. PMID 12644670, Free PMC Article
    5. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Our results suggest that ROP10 negatively regulates ABA responses by specifically and differentially modulating the ABA sensitivity of a subset of genes including protein kinases and zinc-finger family proteins.
      Title: Transcriptome analysis reveals specific modulation of abscisic acid signaling by ROP10 small GTPase in Arabidopsis.
    2. The sequence requirements for association of Arabidopsis ROP9 AND ROP10 with the plasma membrane are reported.
      Title: Association of Arabidopsis type-II ROPs with the plasma membrane requires a conserved C-terminal sequence motif and a proximal polybasic domain.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_114673.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RHO-related protein from plants 10
    NP_566897.1
    • RHO-related protein from plants 10 (ROP10); CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RAC-like 10 (TAIR:AT5G62880.1); Has 24141 Blast hits to 24113 proteins in 664 species: Archae - 8; Bacteria - 48; Metazoa - 12688; Fungi - 3443; Plants - 2679; Viruses - 20; Other Eukaryotes - 5255 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17731337..17733513
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339347.1 → NP_001327655.1  RHO-related protein from plants 10 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LSZ9, A0A654FEQ4

    2. NM_114673.3 → NP_566897.1  RHO-related protein from plants 10 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566897.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82482, Q9SU67
      UniProtKB/TrEMBL
      A0A178VHB5, A0A5S9XJH4, A0A654FEQ4
      Conserved Domains (1) summary
      cd04133
      Location:8 → 180
      Rop_like; Rho-related protein from plants (Rop)-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SU67.2

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