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    PFA-DSP5 Phosphotyrosine protein phosphatases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831509, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PFA-DSP5
    Official Full Name
    Phosphotyrosine protein phosphatases superfamily protein
    Primary source
    TAIR:AT5G16480
    Locus tag
    AT5G16480
    See related
    Araport:AT5G16480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPFA-DSP5; MQK4.21; MQK4_21; plant and fungi atypical dual-specificity phosphatase 5
    Summary
    Encodes an atypical dual-specificity phosphatase.
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    Genomic context

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    See PFA-DSP5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (5381069..5382939, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Putative adipose-regulatory protein (Seipin) Neighboring gene zinc finger (C2H2 type) family protein Neighboring gene RNA-directed DNA polymerase (reverse transcriptase)-related family protein Neighboring gene ROP-interactive CRIB motif-containing protein 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis PFA-DSP-Type Phosphohydrolases Target Specific Inositol Pyrophosphate Messengers. Gaugler P, et al. Biochemistry, 2022 Jun 21. PMID 35640071, Free PMC Article
    2. Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Romá-Mateo C, et al. Mol Genet Genomics, 2011 Apr. PMID 21409566
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_121653.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Phosphotyrosine protein phosphatases superfamily protein
    NP_197152.1
    • Phosphotyrosine protein phosphatases superfamily protein; FUNCTIONS IN: phosphatase activity, protein tyrosine phosphatase activity, phosphoprotein phosphatase activity; INVOLVED IN: dephosphorylation; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein-tyrosine phosphatase, active site (InterPro:IPR016130), Protein-tyrosine phosphatase, dual specificity phosphatase, eukaryotic (InterPro:IPR020428), Protein-tyrosine phosphatase, SIW14-like (InterPro:IPR004861); BEST Arabidopsis thaliana protein match is: Tyrosine phosphatase family protein (TAIR:AT3G02800.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5381069..5382939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343452.1 → NP_001330726.1  Phosphotyrosine protein phosphatases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBP7

    2. NM_121653.4 → NP_197152.1  Phosphotyrosine protein phosphatases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LDU6, Q9FFD7
      UniProtKB/TrEMBL
      A0A178UD17
      Conserved Domains (1) summary
      pfam03162
      Location:14 → 161
      Y_phosphatase2; Tyrosine phosphatase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFD7.1

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