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    FRL1 FRIGIDA like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831493, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FRL1
    Official Full Name
    FRIGIDA like 1
    Primary source
    TAIR:AT5G16320
    Locus tag
    AT5G16320
    See related
    Araport:AT5G16320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    FRIGIDA like 1; MQK4.4; MQK4_4
    Summary
    family member of FRI-related genes that is required for the winter-annual habit. Genbank accession BK004884
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    Genomic context

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    See FRL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (5344495..5346106)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Vps51/Vps67 family (components of vesicular transport) protein Neighboring gene Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1 Neighboring gene ncRNA Neighboring gene NC domain-containing protein-like protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FRIGIDA and related proteins have a conserved central domain and family specific N- and C- terminal regions that are functionally important. Risk JM, et al. Plant Mol Biol, 2010 Jul. PMID 20405310
    2. FRIGIDA-ESSENTIAL 1 interacts genetically with FRIGIDA and FRIGIDA-LIKE 1 to promote the winter-annual habit of Arabidopsis thaliana. Schmitz RJ, et al. Development, 2005 Dec. PMID 16291783
    3. SUPPRESSOR OF FRIGIDA4, encoding a C2H2-Type zinc finger protein, represses flowering by transcriptional activation of Arabidopsis FLOWERING LOCUS C. Kim S, et al. Plant Cell, 2006 Nov. PMID 17138694, Free PMC Article
    4. The FRIGIDA complex activates transcription of FLC, a strong flowering repressor in Arabidopsis, by recruiting chromatin modification factors. Choi K, et al. Plant Cell, 2011 Jan. PMID 21282526, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FRI and FRL1 contain a stable, central domain that is conserved across the FRI superfamily.
      Title: FRIGIDA and related proteins have a conserved central domain and family specific N- and C- terminal regions that are functionally important.
    2. Epistasis analysis between FES1, FRI and FRIGIDA-LIKE 1 (FRL1), indicates that these genes do not function in a linear pathway, but instead act cooperatively to promote the expression of FLC.
      Title: FRIGIDA-ESSENTIAL 1 interacts genetically with FRIGIDA and FRIGIDA-LIKE 1 to promote the winter-annual habit of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_121637.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    FRIGIDA like 1
    NP_197136.1
    • FRIGIDA like 1 (FRL1); CONTAINS InterPro DOMAIN/s: Frigida-like (InterPro:IPR012474); BEST Arabidopsis thaliana protein match is: FRIGIDA like 2 (TAIR:AT1G31814.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5344495..5346106
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121637.4 → NP_197136.1  FRIGIDA like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197136.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FFF1
      UniProtKB/TrEMBL
      A0A5S9Y6Y8
      Conserved Domains (1) summary
      pfam07899
      Location:95 → 368
      Frigida; Frigida-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFF1.1

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