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    AFB5 auxin F-box protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835062, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AFB5
    Official Full Name
    auxin F-box protein 5
    Primary source
    TAIR:AT5G49980
    Locus tag
    AT5G49980
    See related
    Araport:AT5G49980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    auxin F-box protein 5; K9P8.12; K9P8_12
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    Genomic context

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    See AFB5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (20333897..20336671, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ion channel protein Neighboring gene pyridoxin (pyrodoxamine) 5'-phosphate oxidase Neighboring gene Xanthine/uracil permease family protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exogenous Auxin Induces Transverse Microtubule Arrays Through TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX Receptors. True JH, et al. Plant Physiol, 2020 Feb. PMID 31767691, Free PMC Article
    2. The Arabidopsis Auxin Receptor F-Box Proteins AFB4 and AFB5 Are Required for Response to the Synthetic Auxin Picloram. Prigge MJ, et al. G3 (Bethesda), 2016 May 3. PMID 26976444, Free PMC Article
    3. Defining binding efficiency and specificity of auxins for SCF(TIR1/AFB)-Aux/IAA co-receptor complex formation. Lee S, et al. ACS Chem Biol, 2014 Mar 21. PMID 24313839, Free PMC Article
    4. A combinatorial TIR1/AFB-Aux/IAA co-receptor system for differential sensing of auxin. Calderón Villalobos LI, et al. Nat Chem Biol, 2012 Apr 1. PMID 22466420, Free PMC Article
    5. The auxin signalling network translates dynamic input into robust patterning at the shoot apex. Vernoux T, et al. Mol Syst Biol, 2011 Jul 5. PMID 21734647, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Exogenous Auxin Induces Transverse Microtubule Arrays Through TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX Receptors.
      Title: Exogenous Auxin Induces Transverse Microtubule Arrays Through TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX Receptors.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_124377.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables auxin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables auxin receptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables inositol hexakisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in auxin-activated signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of SCF ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    auxin F-box protein 5
    NP_568718.1
    • auxin F-box protein 5 (AFB5); CONTAINS InterPro DOMAIN/s: F-box domain, Skp2-like (InterPro:IPR022364); BEST Arabidopsis thaliana protein match is: RNI-like superfamily protein (TAIR:AT4G24390.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20333897..20336671 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124377.3 → NP_568718.1  auxin F-box protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568718.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YW2, Q9LTX2
      UniProtKB/TrEMBL
      A0A178UB83, A0A5S9YEX6
      Conserved Domains (4) summary
      cd09293
      Location:384 → 538
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:338 → 362
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam18511
      Location:51 → 92
      F-box_5
      pfam18791
      Location:111 → 157
      Transp_inhibit; Transport inhibitor response 1 protein domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTX2.1

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