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    Radical SAM superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818550, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Radical SAM superfamily protein
    Primary source
    TAIR:AT2G39670
    Locus tag
    AT2G39670
    See related
    Araport:AT2G39670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F17A14.4; F17A14_4
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    10
    Sequence:
    Chromosome: 2; NC_003071.7 (16534175..16537318)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cruciferin (DUF506) Neighboring gene botrytis-induced kinase1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ternary complex factor MIP1 leucine-zipper protein (Protein of unknown function, DUF547)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_129523.4
    NM_179988.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA base methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Radical SAM superfamily protein
    NP_565909.1
    • Radical SAM superfamily protein; FUNCTIONS IN: iron-sulfur cluster binding, catalytic activity, RNA methyltransferase activity; INVOLVED IN: rRNA processing; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Ribosomal RNA large subunit methyltransferase RlmN; (InterPro:IPR004383), Radical SAM (InterPro:IPR007197); BEST Arabidopsis thaliana protein match is: Radical SAM superfamily protein (TAIR:AT3G19630.1); Has 7017 Blast hits to 7011 proteins in 2312 species: Archae - 11; Bacteria - 5106; Metazoa - 1; Fungi - 1; Plants - 134; Viruses - 5; Other Eukaryotes - 1759 (source: NCBI BLink).
    NP_850319.1
    • Radical SAM superfamily protein; FUNCTIONS IN: iron-sulfur cluster binding, catalytic activity, RNA methyltransferase activity; INVOLVED IN: rRNA processing; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Ribosomal RNA large subunit methyltransferase RlmN; (InterPro:IPR004383), Radical SAM (InterPro:IPR007197); BEST Arabidopsis thaliana protein match is: Radical SAM superfamily protein (TAIR:AT3G19630.1); Has 6992 Blast hits to 6986 proteins in 2311 species: Archae - 11; Bacteria - 5102; Metazoa - 1; Fungi - 1; Plants - 134; Viruses - 5; Other Eukaryotes - 1738 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16534175..16537318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129523.4 → NP_565909.1  Radical SAM superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565909.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W0C3, O48815, Q940N1
      Conserved Domains (1) summary
      cl18962
      Location:63 → 406
      Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...

    2. NM_179988.1 → NP_850319.1  Radical SAM superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850319.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IVY6
      Conserved Domains (2) summary
      COG0820
      Location:64 → 407
      RlmN; Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37 [Translation, ribosomal structure and biogenesis]
      cl18962
      Location:63 → 409
      Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
    Nucleotide Protein
    Heading Accession and Version

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