Replication interactions
Interaction |
Pubs |
HIV-1 infection (VSV-G pseudotyped) of CEMT4 T cells downregulates plasma membrane expression of SUB1 |
PubMed
|
Knockdown of SUB1 homolog by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 |
PubMed
|
Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Rev
|
rev
|
HIV-1 Rev interacting protein, SUB1 homolog (positive cofactor 4), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells |
PubMed
|
Tat
|
tat
|
Through amino acids 22-91, PC4 binds to the basic TAR binding domain of HIV-1 Tat (amino acids 49-57) and enhances activation of the HIV-1 LTR promoter in a Tat dependent manner |
PubMed
|
Go to the HIV-1, Human Interaction Database