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    SLD2 Fatty acid/sphingolipid desaturase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819228, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SLD2
    Official Full Name
    Fatty acid/sphingolipid desaturase
    Primary source
    TAIR:AT2G46210
    Locus tag
    AT2G46210
    See related
    Araport:AT2G46210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSLD2; sphingoid LCB desaturase 2; T3F17.14
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    Genomic context

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    See SLD2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (18977344..18979309)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U11/U12 small nuclear ribonucleoprotein Neighboring gene DUF2358 family protein (DUF2358) Neighboring gene ncRNA Neighboring gene ABI-1-like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sphingolipid Δ8 unsaturation is important for glucosylceramide biosynthesis and low-temperature performance in Arabidopsis. Chen M, et al. Plant J, 2012 Mar. PMID 22023480
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_130183.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables sphingolipid 8-(E/Z)-desaturase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sphingolipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fatty acid/sphingolipid desaturase
    NP_182144.1
    • Fatty acid/sphingolipid desaturase; FUNCTIONS IN: oxidoreductase activity, oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water, iron ion binding, heme binding; INVOLVED IN: oxidation reduction, fatty acid biosynthetic process, lipid metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Fatty acid desaturase, type 1 (InterPro:IPR005804), Fatty acid/sphingolipid desaturase (InterPro:IPR012171), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: Fatty acid/sphingolipid desaturase (TAIR:AT3G61580.1); Has 5941 Blast hits to 5850 proteins in 906 species: Archae - 2; Bacteria - 1188; Metazoa - 1112; Fungi - 1689; Plants - 939; Viruses - 2; Other Eukaryotes - 1009 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18977344..18979309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130183.4 → NP_182144.1  Fatty acid/sphingolipid desaturase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182144.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EBF7
      UniProtKB/TrEMBL
      A0A178VWW6, A0A5S9X7P2
      Conserved Domains (2) summary
      cd03506
      Location:142 → 404
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
      pfam00173
      Location:11 → 82
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3EBF7.1

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