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    ADF5 actin depolymerizing factor 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816171, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADF5
    Official Full Name
    actin depolymerizing factor 5
    Primary source
    TAIR:AT2G16700
    Locus tag
    AT2G16700
    See related
    Araport:AT2G16700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 5; ACTIN DEPOLYMERIZING FACTOR 5; ATADF5; T24I21.11; T24I21_11
    Summary
    Encodes actin depolymerizing factor 5 (ADF5).
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    Genomic context

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    See ADF5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (7244500..7246069)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene Iron-sulfur cluster biosynthesis family protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis ADF5 promotes stomatal closure by regulating actin cytoskeleton remodeling in response to ABA and drought stress. Qian D, et al. J Exp Bot, 2019 Jan 7. PMID 30476276, Free PMC Article
    2. Higher-Ordered Actin Structures Remodeled by Arabidopsis ACTIN-DEPOLYMERIZING FACTOR5 Are Important for Pollen Germination and Pollen Tube Growth. Zhu J, et al. Mol Plant, 2017 Aug 7. PMID 28606871
    3. Actin-depolymerizing factor2-mediated actin dynamics are essential for root-knot nematode infection of Arabidopsis. Clément M, et al. Plant Cell, 2009 Sep. PMID 19794115, Free PMC Article
    4. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001202606.1
    NM_001335487.1
    NM_127222.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables actin filament binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament bundle assembly IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within actin filament bundle assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    actin depolymerizing factor 5
    NP_001189535.1
    • actin depolymerizing factor 5 (ADF5); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Diguanylate phosphodiesterase, predicted (InterPro:IPR001633), Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 9 (TAIR:AT4G34970.1).
    NP_565390.1
    • actin depolymerizing factor 5 (ADF5); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 9 (TAIR:AT4G34970.1); Has 1273 Blast hits to 1272 proteins in 262 species: Archae - 0; Bacteria - 3; Metazoa - 475; Fungi - 143; Plants - 513; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7244500..7246069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335486.1 → NP_001324825.1  actin depolymerizing factor 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B198

    2. NM_127222.5 → NP_565390.1  actin depolymerizing factor 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565390.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SLE7, Q9ZNT3
      UniProtKB/TrEMBL
      A0A178VPY9, A0A5S9WYS1, A0A654ETC5
      Conserved Domains (1) summary
      PLN03216
      Location:3 → 143
      PLN03216; actin depolymerizing factor; Provisional

    3. NM_001335487.1 → NP_001324824.1  actin depolymerizing factor 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VNB7, F4ILA8
      Conserved Domains (1) summary
      cl15697
      Location:1 → 132
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    4. NM_001202606.1 → NP_001189535.1  actin depolymerizing factor 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189535.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VNB7, F4ILA8
      Conserved Domains (1) summary
      cl15697
      Location:1 → 132
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZNT3.1

    Gene LinkOut

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