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    DNA mismatch repair protein MutS, type 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842815, updated on 18-Sep-2024

    Summary

    Official Full Name
    DNA mismatch repair protein MutS, type 2
    Primary source
    TAIR:AT1G65070
    Locus tag
    AT1G65070
    See related
    Araport:AT1G65070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F16G16.7; F16G16_7
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (24172577..24176356, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene TRAF-like superfamily protein Neighboring gene 4-coumarate:CoA ligase 3 Neighboring gene Membrane insertion protein, OxaA/YidC with tetratricopeptide repeat domain-containing protein Neighboring gene nucleolin Neighboring gene Ubiquitin carboxyl-terminal hydrolase-related protein

    General gene information

    NM_105181.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mismatched DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mismatch repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    DNA mismatch repair protein MutS, type 2
    NP_001185315.1
    • DNA mismatch repair protein MutS, type 2; FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, maintenance of fidelity involved in DNA-dependent DNA replication; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, type 2 (InterPro:IPR005747), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), Smr protein/MutS2 C-terminal (InterPro:IPR002625); BEST Arabidopsis thaliana protein match is: DNA mismatch repair protein MutS, type 2 (TAIR:AT5G54090.1).
    NP_176687.1
    • DNA mismatch repair protein MutS, type 2; FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, maintenance of fidelity involved in DNA-dependent DNA replication; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, type 2 (InterPro:IPR005747), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432); BEST Arabidopsis thaliana protein match is: DNA mismatch repair protein MutS, type 2 (TAIR:AT5G54090.1); Has 13239 Blast hits to 13226 proteins in 2712 species: Archae - 194; Bacteria - 9435; Metazoa - 644; Fungi - 752; Plants - 359; Viruses - 3; Other Eukaryotes - 1852 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24172577..24176356 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198386.2NP_001185315.1  DNA mismatch repair protein MutS, type 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185315.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WFQ3, A0A654EMT5, Q9SS53
      Conserved Domains (1) summary
      PRK00409
      Location:50876
      PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    2. NM_001334190.1NP_001320498.1  DNA mismatch repair protein MutS, type 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMZ1
      Conserved Domains (1) summary
      PRK00409
      Location:50626
      PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
    3. NM_001334191.1NP_001320497.1  DNA mismatch repair protein MutS, type 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMZ6, A0A654EMT5
    4. NM_105181.2NP_176687.1  DNA mismatch repair protein MutS, type 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176687.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EMT5, F4I9U0
      Conserved Domains (2) summary
      PRK00409
      Location:50761
      PRK00409; recombination and DNA strand exchange inhibitor protein; Reviewed
      cl21455
      Location:360567
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases