U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ULP1A UB-like protease 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819876, updated on 18-Sep-2024

    Summary

    Official Symbol
    ULP1A
    Official Full Name
    UB-like protease 1A
    Primary source
    TAIR:AT3G06910
    Locus tag
    AT3G06910
    See related
    Araport:AT3G06910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtULP1a; ELS1; ESD4-LIKE SUMO PROTEASE 1; UB-like protease 1A
    Summary
    Encodes a deSUMOylating enzyme. In vitro it has both peptidase activity and isopeptidase activity: it can cleave the C-terminal residues from SUMO to activate it for attachment to a target protein and it can also act on the isopeptide bond between SUMO and another protein. In vitro assays suggest that this enzyme is active against SUMO1 and SUMO2. It has weak activity with SUMO3 and cannot act on SUMO5. The N-terminal regulatory region of this protein is required for full activity.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ULP1A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (2178630..2181341, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene syntaxin KNOLLE-like protein Neighboring gene ncRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene protein arginine methyltransferase 4B

    General protein information

    Preferred Names
    UB-like protease 1A
    NP_187347.2
    • UB-like protease 1A (ULP1A); CONTAINS InterPro DOMAIN/s: Peptidase C48, SUMO/Sentrin/Ubl1 (InterPro:IPR003653); BEST Arabidopsis thaliana protein match is: Cysteine proteinases superfamily protein (TAIR:AT4G15880.1); Has 1394 Blast hits to 1393 proteins in 209 species: Archae - 0; Bacteria - 2; Metazoa - 593; Fungi - 272; Plants - 373; Viruses - 5; Other Eukaryotes - 149 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2178630..2181341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111571.3NP_187347.2  UB-like protease 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187347.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GYL3, Q9M908
      UniProtKB/TrEMBL
      A0A178VE32, A0A5S9XAF4, A0A654FA41
      Conserved Domains (1) summary
      PLN03189
      Location:37502
      PLN03189; Protease specific for SMALL UBIQUITIN-RELATED MODIFIER (SUMO); Provisional