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    IPT3 isopentenyltransferase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825486, updated on 18-Sep-2024

    Summary

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    Official Symbol
    IPT3
    Official Full Name
    isopentenyltransferase 3
    Primary source
    TAIR:AT3G63110
    Locus tag
    AT3G63110
    See related
    Araport:AT3G63110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATIPT3; isopentenyltransferase 3
    Summary
    Encodes cytokinin synthase involved in cytokinin biosynthesis. IPT3 subcellular localization is modulated by farnesylation- when farnesylated it is localized to the nucleus, otherwise to the chloroplast.
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    Genomic context

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    See IPT3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (23317971..23319636, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene uncharacterized protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene cyclin p1;1 Neighboring gene RAN GTPase activating protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. Galichet A, et al. Plant Physiol, 2008 Mar. PMID 18184738, Free PMC Article
    2. Agrobacterium tumefaciens increases cytokinin production in plastids by modifying the biosynthetic pathway in the host plant. Sakakibara H, et al. Proc Natl Acad Sci U S A, 2005 Jul 12. PMID 15998742, Free PMC Article
    3. Distinct isoprenoid origins of cis- and trans-zeatin biosyntheses in Arabidopsis. Kasahara H, et al. J Biol Chem, 2004 Apr 2. PMID 14726522
    4. Roles of Arabidopsis ATP/ADP isopentenyltransferases and tRNA isopentenyltransferases in cytokinin biosynthesis. Miyawaki K, et al. Proc Natl Acad Sci U S A, 2006 Oct 31. PMID 17062755, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_116176.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables AMP dimethylallyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ATP/ADP dimethylallyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    isopentenyltransferase 3
    NP_567138.1
    • isopentenyltransferase 3 (IPT3); CONTAINS InterPro DOMAIN/s: tRNA isopentenyltransferase (InterPro:IPR002627); BEST Arabidopsis thaliana protein match is: isopentenyltransferase 5 (TAIR:AT5G19040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      23317971..23319636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116176.3 → NP_567138.1  isopentenyltransferase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567138.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93WC9, Q9LYB1
      UniProtKB/TrEMBL
      A0A178V8J2, A0A5S9XN99
      Conserved Domains (1) summary
      cl38936
      Location:12 → 308
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93WC9.1

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