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    ADF3 actin depolymerizing factor 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836110, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADF3
    Official Full Name
    actin depolymerizing factor 3
    Primary source
    TAIR:AT5G59880
    Locus tag
    AT5G59880
    See related
    Araport:AT5G59880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 3; ACTIN DEPOLYMERIZING FACTOR 3; MMN10.4; MMN10_4
    Summary
    Encodes actin depolymerizing factor 3 (ADF3).
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    Genomic context

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    See ADF3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (24120164..24121949)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene histone H2A 6 Neighboring gene ncRNA Neighboring gene actin depolymerizing factor 4 Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis ACTIN-DEPOLYMERIZING FACTOR3 Is Required for Controlling Aphid Feeding from the Phloem. Mondal HA, et al. Plant Physiol, 2018 Jan. PMID 29133373, Free PMC Article
    2. Actin-depolymerizing factor2-mediated actin dynamics are essential for root-knot nematode infection of Arabidopsis. Clément M, et al. Plant Cell, 2009 Sep. PMID 19794115, Free PMC Article
    3. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article
    4. The impact of oxidative stress on Arabidopsis mitochondria. Sweetlove LJ, et al. Plant J, 2002 Dec. PMID 12492832
    5. Identification of proteins that interact with catalytically active calcium-dependent protein kinases from Arabidopsis. Uno Y, et al. Mol Genet Genomics, 2009 Apr. PMID 19130088

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_125381.2
    NM_180896.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    actin depolymerizing factor 3
    NP_568915.2
    • actin depolymerizing factor 3 (ADF3); FUNCTIONS IN: actin binding; INVOLVED IN: response to oxidative stress, response to cadmium ion; LOCATED IN: mitochondrion, intracellular, chloroplast, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 1 (TAIR:AT3G46010.1); Has 1140 Blast hits to 1140 proteins in 246 species: Archae - 0; Bacteria - 3; Metazoa - 383; Fungi - 126; Plants - 514; Viruses - 0; Other Eukaryotes - 114 (source: NCBI BLink).
    NP_851227.1
    • actin depolymerizing factor 3 (ADF3); FUNCTIONS IN: actin binding; INVOLVED IN: response to oxidative stress, response to cadmium ion; LOCATED IN: mitochondrion, intracellular, chloroplast, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 1 (TAIR:AT3G46010.1); Has 1432 Blast hits to 1431 proteins in 264 species: Archae - 0; Bacteria - 5; Metazoa - 599; Fungi - 151; Plants - 515; Viruses - 0; Other Eukaryotes - 162 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24120164..24121949
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180896.3 → NP_851227.1  actin depolymerizing factor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851227.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZSK4
      UniProtKB/TrEMBL
      A0A178U8Q4, A0A5S9YGA2, A0A654GCN1
      Conserved Domains (1) summary
      cd11286
      Location:6 → 138
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    2. NM_125381.2 → NP_568915.2  actin depolymerizing factor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568915.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JXD5
      Conserved Domains (1) summary
      cl15697
      Location:4 → 123
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZSK4.1

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