CBP60G Cam-binding protein 60-like G [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CBP60G
Official Full Name: Cam-binding protein 60-like G
Primary source: TAIR:AT5G26920
Locus tag: AT5G26920
See related: Araport:AT5G26920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Cam-binding protein 60-like G; F2P16.9; F2P16_9
Summary: Encodes a calmodulin-binding protein CBP60g (calmodulin binding protein 60-like.g). The calmodulin-binding domain is located near the N-terminus; calmodulin binding is dependent on Ca(2+). Inducible by both bacterial pathogen and MAMP (microbe-associated molecular pattern) treatments. Bacterial growth is enhanced in cbp60g mutants. cbp60g mutants also show defects in salicylic acid (SA) accumulation and SA signaling.
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Genomic context

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See CBP60G in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 6

Sequence:: Chromosome: 5; NC_003076.8 (9475679..9478777)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Drought attenuates plant defence against bacterial pathogens by suppressing the expression of CBP60g/SARD1 during combined stress.
Title: Drought attenuates plant defence against bacterial pathogens by suppressing the expression of CBP60g/SARD1 during combined stress.
Redundant CAMTA Transcription Factors Negatively Regulate the Biosynthesis of Salicylic Acid and N-Hydroxypipecolic Acid by Modulating the Expression of SARD1 and CBP60g.
Title: Redundant CAMTA Transcription Factors Negatively Regulate the Biosynthesis of Salicylic Acid and N-Hydroxypipecolic Acid by Modulating the Expression of SARD1 and CBP60g.
This work uncovers a virulence strategy in which the Verticillium dahliae secretory protein VdSCP41 directly targets plant transcription factors to inhibit immunity, and reveals Arabidopsis CBP60g, SARD1 and cotton CBP60b as crucial components governing Verticillium dahliae resistance.
Title: The plant-specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity.
SARD1 and CBP60g orchestrate the induction of plant defense regulators in plant immunity.
Title: ChIP-seq reveals broad roles of SARD1 and CBP60g in regulating plant immunity.
Putative components of the CBP60g SARD1 signalling network have been uncovered by co-expression analysis.
Title: Co-expression analysis identifies putative targets for CBP60g and SARD1 regulation.
Overexpression of CBP60g in Arabidopsis enhanced the defense response, hypersensitivity to abscisic acid and tolerance to drought stress. The CBP60g gene acts as a positive regulator in both ABA and SA signaling pathways.
Title: Calmodulin-binding protein CBP60g is a positive regulator of both disease resistance and drought tolerance in Arabidopsis.
CBP60g is playing an important role during the defense response and contributes to production of salicylic acid
Title: CBP60g and SARD1 play partially redundant critical roles in salicylic acid signaling.
studies show that CBP60g constitutes a Ca(2+) link between microbe-associated molecular pattern (MAMP) recognition and salicylic acid accumulation that is important for resistance to Pseudomonas syringae
Title: Arabidopsis CaM binding protein CBP60g contributes to MAMP-induced SA accumulation and is involved in disease resistance against Pseudomonas syringae.

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General gene information

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NM_001203479.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables calmodulin binding	IDA Inferred from Direct Assay more info	PubMed
enables calmodulin binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to hypoxia	IEP Inferred from Expression Pattern more info	PubMed
involved_in cellular response to molecule of bacterial origin	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in defense response to oomycetes	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA-templated transcription	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of salicylic acid biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of salicylic acid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of systemic acquired resistance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in response to UV-B	IDA Inferred from Direct Assay more info	PubMed
involved_in response to bacterium	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to bacterium	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to fungus	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to molecule of bacterial origin	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within salicylic acid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: Cam-binding protein 60-like G

NP_001190408.1

Cam-binding protein 60-like G (CBP60G); FUNCTIONS IN: calmodulin binding; INVOLVED IN: defense response to bacterium, incompatible interaction, salicylic acid biosynthetic process, response to molecule of bacterial origin, response to bacterium; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Calmodulin binding protein-like (InterPro:IPR012416); BEST Arabidopsis thaliana protein match is: Calmodulin-binding protein (TAIR:AT4G25800.2).

NP_198044.2

Cam-binding protein 60-like G (CBP60G); CONTAINS InterPro DOMAIN/s: Calmodulin binding protein-like (InterPro:IPR012416); BEST Arabidopsis thaliana protein match is: Calmodulin-binding protein (TAIR:AT4G25800.2); Has 271 Blast hits to 271 proteins in 14 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 271; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

9475679..9478777

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_122574.4 → NP_198044.2 Cam-binding protein 60-like G [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_198044.2

Status: REVIEWED

UniProtKB/Swiss-Prot

F4K2R6, F4K2R7, Q2VYG1

UniProtKB/TrEMBL

A0A5S9Y7Q3, A0A654G586

Conserved Domains (1) summary

pfam07887
Location:86 → 363

Calmodulin_bind; Calmodulin binding protein-like
NM_001343987.1 → NP_001331616.1 Cam-binding protein 60-like G [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BEE3
NM_001203479.1 → NP_001190408.1 Cam-binding protein 60-like G [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190408.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A5S9Y7Q3

Conserved Domains (1) summary

pfam07887
Location:86 → 360

Calmodulin_bind; Calmodulin binding protein-like