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    ROPGEF14 RHO guanyl-nucleotide exchange factor 14 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840052, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF14
    Official Full Name
    RHO guanyl-nucleotide exchange factor 14
    Primary source
    TAIR:AT1G31650
    Locus tag
    AT1G31650
    See related
    Araport:AT1G31650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF14; F27M3.15; F27M3_15; RHO guanyl-nucleotide exchange factor 14; ROP (rho of plants) guanine nucleotide exchange factor 14
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF14 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (11326251..11330791, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene AGAMOUS-like 86 Neighboring gene AGAMOUS-like 92 Neighboring gene bystin-like protein Neighboring gene Copper amine oxidase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtPRK2 promotes ROP1 activation via RopGEFs in the control of polarized pollen tube growth. Chang F, et al. Mol Plant, 2013 Jul. PMID 23024212, Free PMC Article
    2. Members of a novel class of Arabidopsis Rho guanine nucleotide exchange factors control Rho GTPase-dependent polar growth. Gu Y, et al. Plant Cell, 2006 Feb. PMID 16415208, Free PMC Article
    3. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    4. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102900.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RHO guanyl-nucleotide exchange factor 14
    NP_174446.2
    • RHO guanyl-nucleotide exchange factor 14 (ROPGEF14); CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: RHO guanyl-nucleotide exchange factor 7 (TAIR:AT5G02010.1); Has 302 Blast hits to 301 proteins in 16 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 302; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11326251..11330791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332971.1 → NP_001320846.1  RHO guanyl-nucleotide exchange factor 14 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WGS6, A0A1P8AP33, A0A5S9WJY8

    2. NM_102900.5 → NP_174446.2  RHO guanyl-nucleotide exchange factor 14 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174446.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56WM6, Q8GWY8, Q9C6V5
      UniProtKB/TrEMBL
      A0A178WGS6, A0A5S9WJY8
      Conserved Domains (1) summary
      pfam03759
      Location:136 → 495
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56WM6.1

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