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    NOT2 / NOT3 / NOT5 family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837284, updated on 18-Sep-2024

    Summary

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    Official Full Name
    NOT2 / NOT3 / NOT5 family
    Primary source
    TAIR:AT1G07705
    Locus tag
    AT1G07705
    See related
    Araport:AT1G07705
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Negative on TATA less2a; NOT2a
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (2381555..2386157)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Thioredoxin superfamily protein Neighboring gene ncRNA Neighboring gene Ankyrin repeat family protein Neighboring gene 3-ketoacyl-CoA synthase 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis. Wang L, et al. Plant Cell, 2013 Feb. PMID 23424246, Free PMC Article
    2. Identification of Arabidopsis CCR4-NOT Complexes with Pumilio RNA-Binding Proteins, APUM5 and APUM2. Arae T, et al. Plant Cell Physiol, 2019 Sep 1. PMID 31093672
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At1g07705 protein promotes polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors.
      Title: NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084009.2
    NM_100644.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    NOT2 / NOT3 / NOT5 family
    NP_001077478.1
    • NOT2 / NOT3 / NOT5 family; FUNCTIONS IN: transcription regulator activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NOT2/NOT3/NOT5 (InterPro:IPR007282); BEST Arabidopsis thaliana protein match is: VIRE2 interacting protein 2 (TAIR:AT5G59710.1); Has 3259 Blast hits to 2610 proteins in 429 species: Archae - 0; Bacteria - 983; Metazoa - 821; Fungi - 441; Plants - 185; Viruses - 8; Other Eukaryotes - 821 (source: NCBI BLink).
    NP_563795.3
    • NOT2 / NOT3 / NOT5 family; FUNCTIONS IN: transcription regulator activity; INVOLVED IN: regulation of transcription; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NOT2/NOT3/NOT5 (InterPro:IPR007282); BEST Arabidopsis thaliana protein match is: VIRE2 interacting protein 2 (TAIR:AT5G59710.1); Has 2858 Blast hits to 2245 proteins in 417 species: Archae - 0; Bacteria - 989; Metazoa - 670; Fungi - 343; Plants - 147; Viruses - 8; Other Eukaryotes - 701 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2381555..2386157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084009.2 → NP_001077478.1  NOT2 / NOT3 / NOT5 family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077478.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WP53, A0A5S9T4X7, A8MR45
      Conserved Domains (2) summary
      pfam04153
      Location:481 → 600
      NOT2_3_5; NOT2 / NOT3 / NOT5 family
      cl00160
      Location:116 → 174
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...

    2. NM_100644.3 → NP_563795.3  NOT2 / NOT3 / NOT5 family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563795.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WP53, A0A5S9T4X7, Q0WP31
      Conserved Domains (1) summary
      pfam04153
      Location:481 → 546
      NOT2_3_5; NOT2 / NOT3 / NOT5 family
    Nucleotide Protein
    Heading Accession and Version

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