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    ZFHD1 zinc finger homeodomain 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843296, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZFHD1
    Official Full Name
    zinc finger homeodomain 1
    Primary source
    TAIR:AT1G69600
    Locus tag
    AT1G69600
    See related
    Araport:AT1G69600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA HOMEOBOX PROTEIN 29; ATHB29; F24J1.29; F24J1_29; ZHD11; zinc finger homeodomain 1; zinc finger homeodomain 1; ZINC FINGER HOMEODOMAIN 11
    Summary
    Encodes ZFHD1, a member of the zinc finger homeodomain transcriptional factor family. Binds to the 62 bp promoter region of ERD1 (early responsive to dehydration stress 1). Expression of ZFHD1 is induced by drought, high salinity and abscisic acid.
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    Genomic context

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    See ZFHD1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (26182156..26183546)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CLAVATA3/ESR-RELATED 45 Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene zinc finger FYVE domain protein, putative (DUF1666)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development. Elfving N, et al. Proc Natl Acad Sci U S A, 2011 May 17. PMID 21536906, Free PMC Article
    2. Co-expression of the stress-inducible zinc finger homeodomain ZFHD1 and NAC transcription factors enhances expression of the ERD1 gene in Arabidopsis. Tran LS, et al. Plant J, 2007 Jan. PMID 17233795
    3. Stress induced and nuclear localized HIPP26 from Arabidopsis thaliana interacts via its heavy metal associated domain with the drought stress related zinc finger transcription factor ATHB29. Barth O, et al. Plant Mol Biol, 2009 Jan. PMID 18974936
    4. The Arabidopsis zinc finger-homeodomain genes encode proteins with unique biochemical properties that are coordinately expressed during floral development. Tan QK, et al. Plant Physiol, 2006 Mar. PMID 16428600, Free PMC Article
    5. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger homeodomain 1
    NP_177118.1
    • zinc finger homeodomain 1 (ZFHD1); CONTAINS InterPro DOMAIN/s: Homeobox domain, ZF-HD class (InterPro:IPR006455), ZF-HD homeobox protein, Cys/His-rich dimerisation domain (InterPro:IPR006456), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeobox protein 26 (TAIR:AT5G60480.1); Has 480 Blast hits to 471 proteins in 33 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 480; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      26182156..26183546
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105628.2 → NP_177118.1  zinc finger homeodomain 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177118.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SEZ1
      UniProtKB/TrEMBL
      A0A178WE06, A0A5S9WQX7, A0A7G2E7Q7
      Conserved Domains (2) summary
      TIGR01565
      Location:156 → 213
      homeo_ZF_HD; homeobox domain, ZF-HD class
      pfam04770
      Location:29 → 83
      ZF-HD_dimer; ZF-HD protein dimerization region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SEZ1.1

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