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    TOC120 translocon outer complex protein 120 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820913, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOC120
    Official Full Name
    translocon outer complex protein 120
    Primary source
    TAIR:AT3G16620
    Locus tag
    AT3G16620
    See related
    Araport:AT3G16620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA TRANSLOCON OUTER COMPLEX PROTEIN 120; ATTOC120; translocon outer complex protein 120
    Summary
    component of TOC complex, plastid protein import machinery.
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    Genomic context

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    See TOC120 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (5658317..5662066, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene SNF2 domain-containing protein / helicase domain-containing protein / zinc finger protein-like protein Neighboring gene pentatricopeptide (PPR) repeat-containing protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene translationally controlled tumor protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The toc132toc120 heterozygote mutant of Arabidopsis thaliana accumulates decreased levels of the major chloroplast lipids. Afitlhile M, et al. Phytochemistry, 2021 Apr. PMID 33535085
    2. The major protein import receptor of plastids is essential for chloroplast biogenesis. Bauer J, et al. Nature, 2000 Jan 13. PMID 10646606
    3. Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants. Chen J, et al. Cell, 2023 Oct 26. PMID 37741279, Free PMC Article
    4. Arabidopsis tic110 is essential for the assembly and function of the protein import machinery of plastids. Inaba T, et al. Plant Cell, 2005 May. PMID 15829604, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The toc132toc120 heterozygote mutant of Arabidopsis thaliana accumulates decreased levels of the major chloroplast lipids.
      Title: The toc132toc120 heterozygote mutant of Arabidopsis thaliana accumulates decreased levels of the major chloroplast lipids.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112535.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein targeting to chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    translocon outer complex protein 120
    NP_188284.1
    • translocon outer complex protein 120 (TOC120); FUNCTIONS IN: GTP binding; INVOLVED IN: protein targeting to chloroplast; LOCATED IN: chloroplast outer membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Chloroplast protein import component Toc86/159 (InterPro:IPR005690), AIG1 (InterPro:IPR006703); BEST Arabidopsis thaliana protein match is: multimeric translocon complex in the outer envelope membrane 132 (TAIR:AT2G16640.1); Has 2198 Blast hits to 1948 proteins in 385 species: Archae - 12; Bacteria - 407; Metazoa - 712; Fungi - 212; Plants - 332; Viruses - 5; Other Eukaryotes - 518 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5658317..5662066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112535.4 → NP_188284.1  translocon outer complex protein 120 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188284.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LUS2
      UniProtKB/TrEMBL
      A0A5S9XCZ0, A0A654FHB2
      Conserved Domains (2) summary
      COG5271
      Location:13 → 386
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      TIGR00993
      Location:333 → 1088
      3a0901s04IAP86; chloroplast protein import component Toc86/159, G and M domains
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LUS2.1

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