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    DSEL alpha/beta-Hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827587, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DSEL
    Official Full Name
    alpha/beta-Hydrolases superfamily protein
    Primary source
    TAIR:AT4G18550
    Locus tag
    AT4G18550
    See related
    Araport:AT4G18550
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana DAD1-like seeding establishment-related lipase; AtDSEL; DAD1-like seeding establishment-related lipase; F28J12.210; F28J12_210
    Summary
    DSEL is cytosolic acylhydrolase that shows prefential lipase activity against the sn-1 position of several classes of lipids, including 1,3-diacylglycerols and 1-monoacylglycerols. Overexpression of DSEL leads to increased peroxisome and oil body levels in cotyledons and reduced beta-oxidation activity in seedlings.
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    Genomic context

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    See DSEL in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Sequence:
    Chromosome: 4; NC_003075.7 (10224661..10227140, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene lysine ketoglutarate reductase trans-splicing-like protein, putative (DUF707) Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment. Kim EY, et al. J Plant Physiol, 2011 Sep 15. PMID 21477884
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtDSEL is involved in the negative regulation of seedling establishment by inhibiting the breakdown of storage oils.
      Title: AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_117969.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables monoacylglycerol lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phospholipase A1 activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within diacylglycerol catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid storage IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within monoacylglycerol catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alpha/beta-Hydrolases superfamily protein
    NP_193590.1
    • alpha/beta-Hydrolases superfamily protein; FUNCTIONS IN: triglyceride lipase activity; INVOLVED IN: lipid metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Lipase, class 3 (InterPro:IPR002921); BEST Arabidopsis thaliana protein match is: alpha/beta-Hydrolases superfamily protein (TAIR:AT1G06250.1); Has 1222 Blast hits to 1214 proteins in 260 species: Archae - 0; Bacteria - 234; Metazoa - 8; Fungi - 231; Plants - 573; Viruses - 1; Other Eukaryotes - 175 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10224661..10227140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341292.1 → NP_001328832.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UTS0, A0A1P8B5V5, A0A5S9XTZ0
      Conserved Domains (1) summary
      PLN02571
      Location:30 → 434
      PLN02571; triacylglycerol lipase

    2. NM_001341293.1 → NP_001328833.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B5V6

    3. NM_117969.3 → NP_193590.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193590.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49523, Q8GXS9
      UniProtKB/TrEMBL
      A0A178UTS0
      Conserved Domains (2) summary
      PLN02571
      Location:13 → 417
      PLN02571; triacylglycerol lipase
      cl21494
      Location:23 → 408
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O49523.1

    Gene LinkOut

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