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    ESP4 HEAT repeat-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831597, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ESP4
    Official Full Name
    HEAT repeat-containing protein
    Primary source
    TAIR:AT5G01400
    Locus tag
    AT5G01400
    See related
    Araport:AT5G01400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ENHANCED SILENCING PHENOTYPE 4; T10O8.110; T10O8_110
    Summary
    Encodes a Symplekin/Pta1 homologue which would have the potential to interact with either ESP1 or AtCstF64.
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    Genomic context

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    See ESP4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    26
    Sequence:
    Chromosome: 5; NC_003076.8 (162522..171302, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Homeodomain-like superfamily protein Neighboring gene DNAJ heat shock family protein Neighboring gene Aldolase-type TIM barrel family protein Neighboring gene Glutaredoxin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Herr AJ, et al. Proc Natl Acad Sci U S A, 2006 Oct 10. PMID 17008405, Free PMC Article
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120218.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA processing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulatory ncRNA-mediated post-transcriptional gene silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    part_of mRNA cleavage and polyadenylation specificity factor complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    HEAT repeat-containing protein
    NP_195760.1
    • ENHANCED SILENCING PHENOTYPE 4 (ESP4); FUNCTIONS IN: binding; INVOLVED IN: posttranscriptional gene silencing by RNA, RNA processing; LOCATED IN: mRNA cleavage and polyadenylation specificity factor complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Symplekin tight junction protein C-terminal (InterPro:IPR022075), Armadillo-type fold (InterPro:IPR016024), Protein of unknown function DUF3453 (InterPro:IPR021850); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G27595.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      162522..171302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001342587.1 → NP_001330013.1  HEAT repeat-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U9B4, A0A1P8B9H2

    2. NM_001342588.1 → NP_001330014.1  HEAT repeat-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9H4, A0A5S9Y2M0

    3. NM_120218.2 → NP_195760.1  HEAT repeat-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195760.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y2M0, Q9M033
      Conserved Domains (4) summary
      pfam11935
      Location:95 → 311
      DUF3453; Domain of unknown function (DUF3453)
      pfam12295
      Location:1033 → 1196
      Symplekin_C; Symplekin tight junction protein C terminal
      pfam13646
      Location:46 → 105
      HEAT_2; HEAT repeats
      sd00044
      Location:46 → 74
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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