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    PIP5K3 1-phosphatidylinositol-4-phosphate 5-kinase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817182, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PIP5K3
    Official Full Name
    1-phosphatidylinositol-4-phosphate 5-kinase 3
    Primary source
    TAIR:AT2G26420
    Locus tag
    AT2G26420
    See related
    Araport:AT2G26420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-phosphatidylinositol-4-phosphate 5-kinase 3; T9J22.9; T9J22_9
    Summary
    Encodes a phosphatidylinositol-4-phosphate 5-kinase. Exclusively expressed in roots. Essential for root hair growth.
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    Genomic context

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    See PIP5K3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (11238958..11242963, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene acireductone dioxygenase 3 Neighboring gene IQ-domain 4 Neighboring gene arginine-rich cyclin 1 Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana. Stenzel I, et al. Plant Cell, 2008 Jan. PMID 18178770, Free PMC Article
    2. Phosphatidylinositol phosphate 5-kinase genes respond to phosphate deficiency for root hair elongation in Arabidopsis thaliana. Wada Y, et al. Plant J, 2015 Feb. PMID 25477067
    3. Arabidopsis D6PK is a lipid domain-dependent mediator of root epidermal planar polarity. Stanislas T, et al. Nat Plants, 2015 Nov 2. PMID 27251533
    4. The Arabidopsis Phosphatidylinositol Phosphate 5-Kinase PIP5K3 is a key regulator of root hair tip growth. Kusano H, et al. Plant Cell, 2008 Feb. PMID 18281506, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336067.1
    NM_001336068.1
    NM_001336069.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphatidylinositol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair cell tip growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair elongation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair initiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol-4-phosphate 5-kinase 3
    NP_001318292.1
    • 1-phosphatidylinositol-4-phosphate 5-kinase 3 (PIP5K3); CONTAINS InterPro DOMAIN/s: Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup (InterPro:IPR016034), Phosphatidylinositol-4-phosphate 5-kinase, plant (InterPro:IPR017163), MORN motif (InterPro:IPR003409), Phosphatidylinositol-4-phosphate 5-kinase, core (InterPro:IPR002498); BEST Arabidopsis thaliana protein match is: phosphatidylinositol-4-phosphate 5-kinase 1 (TAIR:AT1G21980.1); Has 28139 Blast hits to 7953 proteins in 632 species: Archae - 0; Bacteria - 4176; Metazoa - 4166; Fungi - 427; Plants - 2573; Viruses - 0; Other Eukaryotes - 16797 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11238958..11242963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336067.1 → NP_001318292.1  1-phosphatidylinositol-4-phosphate 5-kinase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48709
      UniProtKB/TrEMBL
      A0A178VVM9, A0A5S9X1E0

    2. NM_001336068.1 → NP_001324180.1  1-phosphatidylinositol-4-phosphate 5-kinase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVM9, A0A1P8AZC9, A0A5S9X1E0

    3. NM_001336069.1 → NP_001324179.1  1-phosphatidylinositol-4-phosphate 5-kinase 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVM9, A0A1P8AZC9, A0A5S9X1E0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48709.1

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