Armcx3 armadillo repeat containing, X-linked 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Armcx3provided by RGD
Official Full Name: armadillo repeat containing, X-linked 3provided by RGD
Primary source: RGD:1549739
See related: EnsemblRapid:ENSRNOG00000025730 AllianceGenome:RGD:1549739
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to act upstream of or within several processes, including axonal transport of mitochondrion; mitochondrion organization; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; mitochondrial outer membrane; and nucleus. Predicted to be active in mitochondrion. Orthologous to human ARMCX3 (armadillo repeat containing X-linked 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 383.1), Heart (RPKM 305.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: Xq32

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (102230464..102234017)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (97937115..97942098)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (105573909..105577480)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Sox10 is a membrane-associated factor whose transcriptional function is increased by direct interactions with ARMCX3
Title: The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH128942 (e-PCR)
- UniSTS:212250

UniSTS:498498 (e-PCR)
- UniSTS:498498

Armcx3 (e-PCR), detects polymorphism
- UniSTS:498498

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within axonal transport of mitochondrion	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mitochondrion organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in axon cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial outer membrane	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: armadillo repeat-containing X-linked protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001014273.1 → NP_001014295.1 armadillo repeat-containing X-linked protein 3

See identical proteins and their annotated locations for NP_001014295.1

Status: PROVISIONAL

Source sequence(s)

BC083747

UniProtKB/Swiss-Prot

Q5XID7

UniProtKB/TrEMBL

A0A8I6AF34

Related

ENSRNOP00000033859.4, ENSRNOT00000029664.7

Conserved Domains (2) summary

sd00043
Location:156 → 190

ARM; armadillo repeat [structural motif]

pfam04826
Location:112 → 363

Arm_2; Armadillo-like