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    Tdrp testis development related protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498662, updated on 3-Dec-2024

    Summary

    Official Symbol
    Tdrpprovided by RGD
    Official Full Name
    testis development related proteinprovided by RGD
    Primary source
    RGD:1559733
    See related
    EnsemblRapid:ENSRNOG00000027245 AllianceGenome:RGD:1559733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in spermatogenesis. Predicted to be located in mitochondrion. Predicted to be active in cytosol and nucleus. Orthologous to human TDRP (testis development related protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 116.0), Testes (RPKM 109.3) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tdrp in Genome Data Viewer
    Location:
    16q12.5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (82326837..82354861)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (75624047..75652635)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (80729342..80755397)

    Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene glutamate-rich 1 Neighboring gene uncharacterized LOC134482528 Neighboring gene F-box protein 25 Neighboring gene coordinator of PRMT5 and differentiation stimulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in spermatogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    testis development-related protein
    Names
    uncharacterized protein C8orf42 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100791.2NP_001094261.1  testis development-related protein

      See identical proteins and their annotated locations for NP_001094261.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000016
      UniProtKB/Swiss-Prot
      Q498E2
      UniProtKB/TrEMBL
      A0A8L2UPG2, B5DEK3
      Conserved Domains (1) summary
      pfam15683
      Location:38182
      TDRP; Testis development-related protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086034.1 Reference GRCr8

      Range
      82326837..82354861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063275650.1XP_063131720.1  testis development-related protein isoform X1

      Related
      ENSRNOP00000069082.3, ENSRNOT00000082049.3
    2. XM_006253399.3XP_006253461.1  testis development-related protein isoform X2

      See identical proteins and their annotated locations for XP_006253461.1

      UniProtKB/TrEMBL
      A0A8L2QFM2, A6IWE7
      Conserved Domains (1) summary
      pfam15683
      Location:45190
      TDRP; Testis development-related protein
    3. XM_063275651.1XP_063131721.1  testis development-related protein isoform X3

      UniProtKB/Swiss-Prot
      Q498E2
      UniProtKB/TrEMBL
      A0A8L2UPG2, B5DEK3