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    Ccdc113 coiled-coil domain containing 113 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291847, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ccdc113provided by RGD
    Official Full Name
    coiled-coil domain containing 113provided by RGD
    Primary source
    RGD:1565763
    See related
    EnsemblRapid:ENSRNOG00000051510 AllianceGenome:RGD:1565763
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565763
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in centriolar satellite. Predicted to be part of protein-containing complex. Predicted to be active in axoneme and ciliary basal body. Orthologous to human CFAP263 (cilia and flagella associated protein 263). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 110.2), Lung (RPKM 33.8) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc113 in Genome Data Viewer
    Location:
    19p13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (9503062..9522957, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (9497000..9516917, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (9912124..9932183, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene GINS complex subunit 3 Neighboring gene uncharacterized LOC120098510 Neighboring gene serine protease 54 Neighboring gene casein kinase 2 alpha 2 Neighboring gene cilia and flagella associated protein 20

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of mammalian sperm cells identifies new components of the centrosome. Firat-Karalar EN, et al. J Cell Sci, 2014 Oct 1. PMID 25074808, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 113

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427628.1 → NP_001414557.1  coiled-coil domain-containing protein 113

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A0G2JWV4
      Related
      ENSRNOP00000070030.2, ENSRNOT00000085144.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      9503062..9522957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098119.2 → XP_038954047.1  coiled-coil domain-containing protein 113 isoform X1

      UniProtKB/TrEMBL
      A6JY03
      Conserved Domains (1) summary
      pfam13870
      Location:135 → 309
      DUF4201; Domain of unknown function (DUF4201)

    2. XM_039098120.2 → XP_038954048.1  coiled-coil domain-containing protein 113 isoform X2

      Conserved Domains (1) summary
      pfam13870
      Location:19 → 191
      DUF4201; Domain of unknown function (DUF4201)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001191598.1: Suppressed sequence

      Description
      NM_001191598.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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