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    Efr3b EFR3 homolog B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313928, updated on 9-Dec-2024

    Summary

    Official Symbol
    Efr3bprovided by RGD
    Official Full Name
    EFR3 homolog Bprovided by RGD
    Primary source
    RGD:1310845
    See related
    EnsemblRapid:ENSRNOG00000012950 AllianceGenome:RGD:1310845
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310845
    Summary
    Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in actin cytoskeleton and cytosol. Predicted to be active in plasma membrane. Orthologous to human EFR3B (EFR3 homolog B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 186.0), Muscle (RPKM 40.6) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Efr3b in Genome Data Viewer
    Location:
    6q14
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (32664593..32740417, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (26947436..27021113, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (28390541..28464174, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene DNA methyltransferase 3 alpha Neighboring gene uncharacterized LOC120103494 Neighboring gene Yip1 domain family, member 4 like 1 Neighboring gene uncharacterized LOC120103495 Neighboring gene proopiomelanocortin Neighboring gene DnaJ heat shock protein family (Hsp40) member C27 Neighboring gene general transcription factor IIH subunit 5-like Neighboring gene cytochrome c oxidase subunit 7B, pseudogene 3 Neighboring gene adenylate cyclase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within social behavior ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within transmission of nerve impulse ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427261.2NP_001414190.1  protein EFR3 homolog B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I5ZM57, F1LTW9
      Related
      ENSRNOP00000078976.2, ENSRNOT00000097849.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      32664593..32740417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113097.2XP_038969025.2  protein EFR3 homolog B isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZM57