Mex3a mex-3 RNA binding family member A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mex3aprovided by RGD
Official Full Name: mex-3 RNA binding family member Aprovided by RGD
Primary source: RGD:1564904
See related: EnsemblRapid:ENSRNOG00000058654 AllianceGenome:RGD:1564904
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564904
Summary: Predicted to enable RNA binding activity. Predicted to be located in P-body and cytosol. Orthologous to human MEX3A (mex-3 RNA binding family member A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 31.8), Uterus (RPKM 17.1) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (176287900..176297369)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (173990098..173999567)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (187893678..187902546)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in P-body	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RNA-binding protein MEX3A

Names: mex3 homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398739.1 → NP_001385668.1 RNA-binding protein MEX3A

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

UniProtKB/TrEMBL

A0A1B0GWR7

Related

ENSRNOP00000075996.2, ENSRNOT00000093014.3

Conserved Domains (3) summary

cd16518
Location:469 → 509

RING-HC_MEX3; RING finger, HC subclass, found in RNA-binding proteins of the evolutionarily-conserved MEX-3 family

cd22423
Location:132 → 204

KH-I_MEX3_rpt1; first type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins

cd22424
Location:221 → 292

KH-I_MEX3_rpt2; second type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins