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    Tmem229b transmembrane protein 229B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 503035, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem229bprovided by RGD
    Official Full Name
    transmembrane protein 229Bprovided by RGD
    Primary source
    RGD:1562622
    See related
    EnsemblRapid:ENSRNOG00000010646 AllianceGenome:RGD:1562622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562622
    Summary
    Predicted to act upstream of or within macrophage activation and response to bacterium. Predicted to be located in membrane. Orthologous to human TMEM229B (transmembrane protein 229B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 133.5), Spleen (RPKM 112.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem229b in Genome Data Viewer
    Location:
    6q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (103509457..103552600, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (97771645..97819582, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (102152146..102196372, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene pleckstrin 2 Neighboring gene uncharacterized LOC102547797 Neighboring gene pleckstrin homology, MyTH4 and FERM domain containing H1 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class H Neighboring gene branched chain ketoacid dehydrogenase kinase, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within macrophage activation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within response to bacterium ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 229B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001434333.1 → NP_001421262.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    2. NM_001434334.1 → NP_001421263.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    3. NM_001434336.1 → NP_001421265.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    4. NM_001434337.1 → NP_001421266.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    5. NM_001434338.1 → NP_001421267.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    6. NM_001434339.1 → NP_001421268.1  transmembrane protein 229B

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      103509457..103552600 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017594316.2 → XP_017449805.1  transmembrane protein 229B isoform X1

      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    2. XM_017594325.3 → XP_017449814.1  transmembrane protein 229B isoform X1

      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    3. XM_017594319.3 → XP_017449808.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3
      Related
      ENSRNOP00000100204.1, ENSRNOT00000137203.1
      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    4. XM_017594313.3 → XP_017449802.1  transmembrane protein 229B isoform X1

      Related
      ENSRNOP00000097942.1, ENSRNOT00000119192.2
      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    5. XM_063262352.1 → XP_063118422.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3

    6. XM_063262349.1 → XP_063118419.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3
      Related
      ENSRNOP00000014132.2, ENSRNOT00000014132.6

    7. XM_063262351.1 → XP_063118421.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3
      Related
      ENSRNOP00000086127.1, ENSRNOT00000098038.2

    8. XM_063262350.1 → XP_063118420.1  transmembrane protein 229B isoform X1

    9. XM_063262348.1 → XP_063118418.1  transmembrane protein 229B isoform X1

    10. XM_017594315.3 → XP_017449804.1  transmembrane protein 229B isoform X1

      Related
      ENSRNOP00000102485.1, ENSRNOT00000150319.1
      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    11. XM_039112767.2 → XP_038968695.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3
      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    12. XM_039112770.2 → XP_038968698.1  transmembrane protein 229B isoform X1

      UniProtKB/TrEMBL
      A6HCF8, D4ACC3
      Related
      ENSRNOP00000110994.1, ENSRNOT00000147886.1
      Conserved Domains (1) summary
      cl26964
      Location:50 → 135
      ABC_trans_CmpB; Putative ABC-transporter type IV

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001109359.2: Suppressed sequence

      Description
      NM_001109359.2: This RefSeq was removed because currently there is no support for the transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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