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    Ust5r integral membrane transport protein UST5r [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171398, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ust5rprovided by RGD
    Official Full Name
    integral membrane transport protein UST5rprovided by RGD
    Primary source
    RGD:620985
    See related
    EnsemblRapid:ENSRNOG00000061890 AllianceGenome:RGD:620985
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in organic anion transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to human SLC22A9 (solute carrier family 22 member 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 256.6) and Kidney (RPKM 217.1) See more
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    Genomic context

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    See Ust5r in Genome Data Viewer
    Location:
    1q43
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (214640172..214716024, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (205210558..205286868, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (224457895..224533994, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22, member 27 like, pseudogene 1 Neighboring gene uncharacterized LOC134483964 Neighboring gene integral membrane transport protein UST4r Neighboring gene solute carrier family 22, member 25 Neighboring gene enhancer of rudimentary homolog Neighboring gene solute carrier family 22 member 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC114265

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    integral membrane transport protein UST5r

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_134380.2 → NP_599207.2  integral membrane transport protein UST5r

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A9K3Y8C4, F7F2E0, Q4KM07, Q8VDA8
      Related
      ENSRNOP00000039430.5, ENSRNOT00000051289.7
      Conserved Domains (1) summary
      cd17374
      Location:109 → 516
      MFS_OAT; Organic anion transporters of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      214640172..214716024 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089501.2 → XP_038945429.1  integral membrane transport protein UST5r isoform X3

      Conserved Domains (1) summary
      cl28910
      Location:9 → 302
      MFS; Major Facilitator Superfamily

    2. XM_039089530.2 → XP_038945458.1  integral membrane transport protein UST5r isoform X4

      Conserved Domains (1) summary
      cl28910
      Location:1 → 285
      MFS; Major Facilitator Superfamily

    3. XM_039089458.2 → XP_038945386.1  integral membrane transport protein UST5r isoform X2

      Conserved Domains (1) summary
      cl28910
      Location:1 → 334
      MFS; Major Facilitator Superfamily

    4. XM_039089572.2 → XP_038945500.1  integral membrane transport protein UST5r isoform X5

      UniProtKB/TrEMBL
      A0A0G2K2H1
      Related
      ENSRNOP00000072241.2, ENSRNOT00000077408.3
      Conserved Domains (1) summary
      cl28910
      Location:109 → 464
      MFS; Major Facilitator Superfamily

    5. XM_063276288.1 → XP_063132358.1  integral membrane transport protein UST5r isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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