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    CG10663 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39421, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10663provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036287
    Locus tag
    Dmel_CG10663
    See related
    AllianceGenome:FB:FBgn0036287
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT29868; Dmel\CG10663; SP30
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10663 in Genome Data Viewer
    Location:
    69C2-69C2; 3-38 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12474418..12485035, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12467518..12478135, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene eyegone Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45681 Neighboring gene antisense RNA:CR45682 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila, an emerging model for cardiac disease. Bier E, et al. Gene, 2004 Nov 10. PMID 15527959
    2. Transcriptome Analysis of Drosophila melanogaster Third Instar Larval Ring Glands Points to Novel Functions and Uncovers a Cytochrome p450 Required for Development. Christesen D, et al. G3 (Bethesda), 2017 Feb 9. PMID 27974438, Free PMC Article
    3. Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies. Nakano S, et al. PLoS Genet, 2023 Jun. PMID 37319131, Free PMC Article
    4. Oviposition behaviour in Drosophila melanogaster: Genetic and behavioural decoupling between oviposition acceptance and preference for natural fruits. Fanara JJ, et al. J Evol Biol, 2023 Jan. PMID 36357966
    5. A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience. Evans CJ, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561251, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10663-PB
    CG10663-PD
    NP_001097592.1
    NP_001097593.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12474418..12485035 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104123.2 → NP_001097593.2  uncharacterized protein Dmel_CG10663, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097593.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNS0
      Conserved Domains (2) summary
      smart00020
      Location:506 → 735
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:507 → 735
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. NM_001104122.3 → NP_001097592.1  uncharacterized protein Dmel_CG10663, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097592.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8JNS0
      Conserved Domains (2) summary
      smart00020
      Location:506 → 735
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:507 → 735
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8JNS0 A8JNS0

    Gene LinkOut

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