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    CG33098 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326253, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG33098provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053098
    Locus tag
    Dmel_CG33098
    See related
    AllianceGenome:FB:FBgn0053098
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT09395; BcDNA:RH08915; CG17756; CT39356; Dmel\CG33098; RLC3
    Summary
    Predicted to enable myosin heavy chain binding activity. Predicted to be involved in locomotion and post-embryonic development. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33098 in Genome Data Viewer
    Location:
    87B9-87B9; 3-52 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12387188..12388794)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8212910..8214516)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glutathione S transferase D11 Neighboring gene Sol1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 9f3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Thirteen is enough: the myosins of Dictyostelium discoideum and their light chains. Kollmar M. BMC Genomics, 2006 Jul 20. PMID 16857047, Free PMC Article
    2. Contribution of Orb2A stability in regulated amyloid-like oligomerization of Drosophila Orb2. White-Grindley E, et al. PLoS Biol, 2014 Feb. PMID 24523662, Free PMC Article
    3. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in locomotion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in post-embryonic development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of myosin II complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33098-PB
    CG33098-PC
    CG33098-PD
    CG33098-PE
    CG33098-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12387188..12388794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001275573.2 → NP_001262502.1  uncharacterized protein Dmel_CG33098, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262502.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VG88
      Conserved Domains (1) summary
      COG5126
      Location:76 → 195
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    2. NM_001275572.2 → NP_001262501.1  uncharacterized protein Dmel_CG33098, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262501.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VG88
      Conserved Domains (1) summary
      COG5126
      Location:76 → 195
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    3. NM_176480.2 → NP_788657.1  uncharacterized protein Dmel_CG33098, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788657.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VG88
      Related
      FBpp0082051
      Conserved Domains (1) summary
      COG5126
      Location:76 → 195
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

    4. NM_176481.1 → NP_788658.1  uncharacterized protein Dmel_CG33098, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788658.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T4H3
      Related
      FBpp0082052, FBtr0082580
      Conserved Domains (2) summary
      COG5126
      Location:76 → 171
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd00051
      Location:85 → 143
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    5. NM_176482.2 → NP_788659.1  uncharacterized protein Dmel_CG33098, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788659.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86B93, Q8IGI9
      Related
      FBpp0082050
      Conserved Domains (2) summary
      PTZ00184
      Location:9 → 155
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:19 → 77
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q86B93 Q86B93
    Q8IGI9 Q8IGI9
    Q8T4H3 Q8T4H3
    Q9VG88 Q9VG88

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