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    CG7329 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34457, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG7329provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032271
    Locus tag
    Dmel_CG7329
    See related
    AllianceGenome:FB:FBgn0032271
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7329; ORE-4
    Summary
    Predicted to enable triacylglycerol lipase activity. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 8. Orthologous to human LIPK (lipase family member K); LIPM (lipase family member M); and LIPN (lipase family member N). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7329 in Genome Data Viewer
    Location:
    32A2-32A2; 2-43 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10629352..10638471, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10629352..10638471, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Tripartite motif containing 9 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45351 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of unannotated exons of low abundance transcripts in Drosophila melanogaster and cloning of a new serine protease gene upregulated upon injury. Maia RM, et al. BMC Genomics, 2007 Jul 24. PMID 17650329, Free PMC Article
    2. Comparative and functional genomics of lipases in holometabolous insects. Horne I, et al. Insect Biochem Mol Biol, 2009 Aug. PMID 19540341
    3. A Superfamily-wide Activity Atlas of Serine Hydrolases in Drosophila melanogaster. Kumar K, et al. Biochemistry, 2021 Apr 27. PMID 33827210, Free PMC Article
    4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables triacylglycerol lipase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7329-PA
    CG7329-PB
    NP_001260357.1
    NP_609425.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10629352..10638471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273428.2 → NP_001260357.1  uncharacterized protein Dmel_CG7329, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260357.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3X7, Q9VKT2
      Conserved Domains (3) summary
      pfam00561
      Location:77 → 371
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam04083
      Location:42 → 96
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      cl21494
      Location:73 → 239
      Abhydrolase; alpha/beta hydrolases

    2. NM_135581.2 → NP_609425.1  uncharacterized protein Dmel_CG7329, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609425.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T3X7, Q9VKT2
      Related
      FBpp0079720
      Conserved Domains (3) summary
      pfam00561
      Location:77 → 371
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam04083
      Location:42 → 96
      Abhydro_lipase; Partial alpha/beta-hydrolase lipase region
      cl21494
      Location:73 → 239
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3X7 Q8T3X7
    Q9VKT2 Q9VKT2

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