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    Mob2 Mob2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39293, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mob2provided by FlyBase
    Official Full Name
    Mob2provided by FlyBase
    Primary source
    FLYBASE:FBgn0259481
    Locus tag
    Dmel_CG11711
    See related
    AllianceGenome:FB:FBgn0259481
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH13236; BEST:GH06341; CG11711; CG11712; Dmel\CG11711; Dmob1; dmob2; Dmob2; DMob2; gh06341; Mob1; MobI; trezor
    Summary
    Enables protein kinase binding activity. Involved in several processes, including long-term memory; negative regulation of synaptic assembly at neuromuscular junction; and rhabdomere development. Located in several cellular components, including cell hair; plasma membrane; and rhabdomere. Is expressed in several structures, including adult head; gland; imaginal disc; larval central nervous system; and larval ventral nerve cord. Orthologous to human MOB2 (MOB kinase activator 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Mob2 in Genome Data Viewer
    Location:
    68C12-68C13; 3-36 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11522757..11562233, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11515857..11555333, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Salivary gland secretion 3 Neighboring gene uncharacterized protein Neighboring gene alpha-L-fucosidase Neighboring gene mir-4968 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in long-term memory IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of synaptic assembly at neuromuscular junction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in rhabdomere development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cell hair IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in rhabdomere IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    Mob2
    Names
    CG11711-PA
    CG11711-PB
    CG11711-PC
    CG11711-PD
    CG11711-PE
    Mob2-PA
    Mob2-PB
    Mob2-PC
    Mob2-PD
    Mob2-PE

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11522757..11562233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168461.2NP_729715.2  Mob2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729715.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088371, FBtr0089332
      Conserved Domains (1) summary
      pfam03637
      Location:328494
      Mob1_phocein; Mob1/phocein family
    2. NM_168462.2NP_729716.1  Mob2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729716.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4U9
      Related
      FBpp0088372
      Conserved Domains (1) summary
      pfam03637
      Location:137303
      Mob1_phocein; Mob1/phocein family
    3. NM_140217.2NP_648474.1  Mob2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648474.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQG1
      Related
      FBpp0088369
      Conserved Domains (1) summary
      pfam03637
      Location:31197
      Mob1_phocein; Mob1/phocein family
    4. NM_168460.2NP_729714.1  Mob2, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729714.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5BHY7, Q8IGB4, Q8IQG1, Q8IQG2, Q9VTJ6, Q9VTJ7
      Related
      FBpp0088370
      Conserved Domains (1) summary
      pfam03637
      Location:166332
      Mob1_phocein; Mob1/phocein family
    5. NM_001274784.1NP_001261713.1  Mob2, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261713.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D6W4U9
      Conserved Domains (1) summary
      pfam03637
      Location:137303
      Mob1_phocein; Mob1/phocein family