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    Glyat Glycine N-acyltransferase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3885627, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Glyatprovided by FlyBase
    Official Full Name
    Glycine N-acyltransferaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0054010
    Locus tag
    Dmel_CG34010
    See related
    AllianceGenome:FB:FBgn0054010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BP1022; CG34010; dGLYAT; Dmel\CG34010; GLYAT
    Summary
    Predicted to enable glycine N-acyltransferase activity. Orthologous to several human genes including GLYAT (glycine-N-acyltransferase); GLYATL1 (glycine-N-acyltransferase like 1); and GLYATL1B (glycine-N-acyltransferase like 1B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Glyat in Genome Data Viewer
    Location:
    28D3-28D3; 2-29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8009603..8010652, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8009603..8010652, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Serpin 28Dc Neighboring gene uncharacterized protein Neighboring gene Transglutaminase Neighboring gene uncharacterized protein Neighboring gene barrier to autointegration factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GLYAT regulates JNK-mediated cell death in Drosophila. Ren P, et al. Sci Rep, 2017 Jul 12. PMID 28701716, Free PMC Article
    2. Drosophila Serpin-28D regulates hemolymph phenoloxidase activity and adult pigmentation. Scherfer C, et al. Dev Biol, 2008 Nov 15. PMID 18801354
    3. dGLYAT modulates Gadd45-mediated JNK activation and cell invasion. Xu M, et al. Cell Div, 2022 Aug 6. PMID 35933447, Free PMC Article
    4. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Yandell M, et al. Proc Natl Acad Sci U S A, 2005 Feb 1. PMID 15668397, Free PMC Article
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycine N-acyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    glycine N-acyltransferase
    Names
    CG34010-PA
    Glyat-PA
    NP_001033883.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8009603..8010652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038794.4 → NP_001033883.2  glycine N-acyltransferase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033883.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A2VEL1, Q2PDV0
      Conserved Domains (2) summary
      COG0456
      Location:155 → 264
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      cl17182
      Location:189 → 272
      NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2PDV0 Q2PDV0

    Gene LinkOut

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