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    CG30427 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37986, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30427provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0043792
    Locus tag
    Dmel_CG30427
    See related
    AllianceGenome:FB:FBgn0043792
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:LD36843; CG18680; CG2858; Dmel\CG30427
    Summary
    Predicted to enable alcohol-forming very long-chain fatty acyl-CoA reductase activity. Involved in determination of adult lifespan. Predicted to be active in peroxisome. Is expressed in several structures, including adult head; antennal primordium; gut section; head epidermis primordium; and somatic precursor cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30427 in Genome Data Viewer
    Location:
    60E5-60E5; 2-107 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24928747..24937477, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20816270..20825000, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Na channel protein 60E Neighboring gene Ribosomal protein L41 Neighboring gene painless Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Troponin C-akin-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of exon-intron structure and alternative splicing in fruit flies and malarial mosquito genomes. Malko DB, et al. Genome Res, 2006 Apr. PMID 16520458, Free PMC Article
    2. Mining gene expression data for pollutants (dioxin, toluene, formaldehyde) and low dose of gamma-irradiation. Moskalev A, et al. PLoS One, 2014. PMID 24475070, Free PMC Article
    3. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
    4. Gene expression and morphogenesis during the deposition of Drosophila wing cuticle. Adler PN. Fly (Austin), 2017 Jul 3. PMID 28631994, Free PMC Article
    5. Effective but costly, evolved mechanisms of defense against a virulent opportunistic pathogen in Drosophila melanogaster. Ye YH, et al. PLoS Pathog, 2009 Apr. PMID 19381251, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables alcohol-forming very long-chain fatty acyl-CoA reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in long-chain fatty-acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30427-PA
    CG30427-PB
    CG30427-PC
    CG30427-PD
    CG30427-PE
    CG30427-PF
    CG30427-PG

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24928747..24937477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166697.3 → NP_726498.1  uncharacterized protein Dmel_CG30427, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726498.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D9PTW2, Q8MMC6
      Related
      FBpp0072319
      Conserved Domains (2) summary
      cd05236
      Location:15 → 321
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      pfam03015
      Location:364 → 453
      Sterile; Male sterility protein

    2. NM_001169827.2 → NP_001163298.1  uncharacterized protein Dmel_CG30427, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163298.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI89, Q960T0, Q9W0Y5
      Conserved Domains (2) summary
      cd05236
      Location:15 → 330
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      pfam03015
      Location:363 → 454
      Sterile; Male sterility protein

    3. NM_001259583.1 → NP_001246512.1  uncharacterized protein Dmel_CG30427, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246512.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D9PTW2, Q8MMC6
      Conserved Domains (2) summary
      cd05236
      Location:15 → 321
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      pfam03015
      Location:364 → 453
      Sterile; Male sterility protein

    4. NM_138136.4 → NP_611980.1  uncharacterized protein Dmel_CG30427, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611980.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI89, Q960T0, Q9W0Y5
      Related
      FBpp0072320
      Conserved Domains (2) summary
      cd05236
      Location:15 → 330
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      pfam03015
      Location:363 → 454
      Sterile; Male sterility protein

    5. NM_001169828.1 → NP_001163299.1  uncharacterized protein Dmel_CG30427, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163299.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BI89, Q960T0, Q9W0Y5
      Conserved Domains (2) summary
      cd05236
      Location:15 → 330
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      pfam03015
      Location:363 → 454
      Sterile; Male sterility protein

    6. NM_166698.3 → NP_726499.1  uncharacterized protein Dmel_CG30427, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726499.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8W1
      Related
      FBpp0072321
      Conserved Domains (3) summary
      cd05236
      Location:15 → 329
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      COG0451
      Location:15 → 341
      WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
      pfam03015
      Location:363 → 454
      Sterile; Male sterility protein

    7. NM_166699.1 → NP_726500.1  uncharacterized protein Dmel_CG30427, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726500.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8W1
      Related
      FBpp0072322, FBtr0072416
      Conserved Domains (3) summary
      cd05236
      Location:15 → 329
      FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
      COG0451
      Location:15 → 341
      WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
      pfam03015
      Location:363 → 454
      Sterile; Male sterility protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E8W1 Q0E8W1
    Q5BI89 Q5BI89
    Q8MMC6 Q8MMC6
    Q9W0Y5 Q9W0Y5

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