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    NdufA3 NADH:ubiquinone oxidoreductase subunit A3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50405, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NdufA3provided by FlyBase
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit A3provided by FlyBase
    Primary source
    FLYBASE:FBgn0040931
    Locus tag
    Dmel_CG9034
    See related
    AllianceGenome:FB:FBgn0040931
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH45008; CG9034; Dmel\CG9034; GH20078; NDUFA3; prto
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; epithelium; somatic mesoderm; and visceral mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See NdufA3 in Genome Data Viewer
    Location:
    8C14-8C14; 1-26 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9159514..9160052, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9053547..9054085, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Oligosaccharyltransferase 48kD subunit Neighboring gene Dorsal interacting protein 1 Neighboring gene Zpr1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Page SL, et al. Genetics, 2000 Aug. PMID 10924472, Free PMC Article
    2. Purriato is a conserved small open reading frame gene that interacts with the CASA pathway to regulate muscle homeostasis and epithelial tissue growth in Drosophila. Pueyo JI, et al. Front Cell Dev Biol, 2023. PMID 36968202, Free PMC Article
    3. The mei-P26 gene encodes a RING finger B-box coiled-coil-NHL protein that regulates seizure susceptibility in Drosophilia. Glasscock E, et al. Genetics, 2005 Aug. PMID 15937125, Free PMC Article
    4. FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. Krause SA, et al. Nucleic Acids Res, 2022 Jan 7. PMID 34718735, Free PMC Article
    5. The pleiotropic functions of Pri smORF peptides synchronize leg development regulators. Markus D, et al. PLoS Genet, 2023 Oct. PMID 37903161, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    part_of respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH:ubiquinone oxidoreductase subunit A3
    Names
    CG9034-PA
    CG9034-PB
    NdufA3-PA
    NdufA3-PB
    purriato

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9159514..9160052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298108.1 → NP_001285037.1  NADH:ubiquinone oxidoreductase subunit A3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285037.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W380

    2. NM_144281.4 → NP_652538.1  NADH:ubiquinone oxidoreductase subunit A3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652538.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9W380
      Related
      FBpp0071278
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W380 Q9W380

    Gene LinkOut

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