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    Zfp687 zinc finger protein 687 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100363361, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Zfp687provided by RGD
    Official Full Name
    zinc finger protein 687provided by RGD
    Primary source
    RGD:2323182
    See related
    EnsemblRapid:ENSRNOG00000021026 AllianceGenome:RGD:2323182
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in Paget's disease of bone 6. Orthologous to human ZNF687 (zinc finger protein 687). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Adrenal (RPKM 31.1), Thymus (RPKM 27.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp687 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (185261903..185270651, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (182572893..182581641, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (196172266..196180946, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene regulatory factor X5 Neighboring gene phosphatidylinositol 4-kinase beta Neighboring gene uncharacterized LOC102547008 Neighboring gene proteasome 26S subunit ubiquitin receptor, non-ATPase 4 Neighboring gene uncharacterized LOC134485649

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 687

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427731.1 → NP_001414660.1  zinc finger protein 687

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      D3ZT56
      Related
      ENSRNOP00000028553.4, ENSRNOT00000028553.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      185261903..185270651 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232935.4 → XP_006232997.1  zinc finger protein 687 isoform X1

      UniProtKB/TrEMBL
      D3ZT56
      Conserved Domains (3) summary
      sd00017
      Location:964 → 984
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:794 → 876
      zf-C2H2_8; C2H2-type zinc ribbon
      pfam16622
      Location:1129 → 1157
      zf-C2H2_11; zinc-finger C2H2-type

    2. XM_002729081.6 → XP_002729127.1  zinc finger protein 687 isoform X1

      UniProtKB/TrEMBL
      D3ZT56
      Conserved Domains (3) summary
      sd00017
      Location:964 → 984
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:794 → 876
      zf-C2H2_8; C2H2-type zinc ribbon
      pfam16622
      Location:1129 → 1157
      zf-C2H2_11; zinc-finger C2H2-type

    3. XM_006232934.4 → XP_006232996.1  zinc finger protein 687 isoform X1

      UniProtKB/TrEMBL
      D3ZT56
      Conserved Domains (3) summary
      sd00017
      Location:964 → 984
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:794 → 876
      zf-C2H2_8; C2H2-type zinc ribbon
      pfam16622
      Location:1129 → 1157
      zf-C2H2_11; zinc-finger C2H2-type
    Nucleotide Protein Strain
    Heading Accession and Version

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